ID Q8PY13_METMA Unreviewed; 523 AA.
AC Q8PY13;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MM_1053 {ECO:0000313|EMBL:AAM30749.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM30749.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM30749.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; AE008384; AAM30749.1; -; Genomic_DNA.
DR RefSeq; WP_011033002.1; NC_003901.1.
DR AlphaFoldDB; Q8PY13; -.
DR GeneID; 82160080; -.
DR KEGG; mma:MM_1053; -.
DR PATRIC; fig|192952.21.peg.1234; -.
DR eggNOG; arCOG02341; Archaea.
DR HOGENOM; CLU_600812_0_0_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR012029; UCP006557.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF09884; DUF2111; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF08447; PAS_3; 2.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
FT DOMAIN 140..177
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 181..233
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 273..310
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 314..366
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
SQ SEQUENCE 523 AA; 59115 MW; 62F877534525F8C0 CRC64;
MISEDAGPEE LEAIAVAVHS LVGLPTTIRS LKRKGLRLEN GKIIDRDYTG PVLEEVLRTG
KTVRGVPKGG TYLGRNVAVS PIFSEDGKVV AAIGIVDLLS VLKMQETIRT VVNNSPAVVF
LWRNEEKWPA EFVSENVVKF GYTVEDFISG NFLYGDIIHP EDRNRVKEEL KTRIRRGEVD
FNTGYRIFTK AGDVRWVNER AFIQRNREGE ITHIQGLVLD ITEDKEKEEA LSKSIEMQSM
LRTIINNSQA IAFLWENKEN LPAEYVSENV TQLGYKVEDF ISGKVLYGDI IHKDDINKVN
ETLKRSIAEG QGSFGIEYRI YTGEGRMLWV EERVFVQRDE EGRATHLQGL VVDITERKEA
QKMLEIQREL GAKLNTTWNL HAILNMVLDA CLQINGIDAG GVYIRDELLD QINLVQSRGI
SPEFKEKVSR FKADSNEAKQ VWAEKPIYSM DFYSDKMAEA ARKEGIKAVA VIPLKYSNEI
IGSLNFASHT LDKIPWNIRN FLESIALQVV SHIAPVCIQA DLS
//
