ID Q8PZH5_METMA Unreviewed; 901 AA.
AC Q8PZH5;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 137.
DE SubName: Full=Hypothetical sensory transduction histidine kinase {ECO:0000313|EMBL:AAM30214.1};
DE EC=2.7.3.- {ECO:0000313|EMBL:AAM30214.1};
GN OrderedLocusNames=MM_0518 {ECO:0000313|EMBL:AAM30214.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM30214.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM30214.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
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DR EMBL; AE008384; AAM30214.1; -; Genomic_DNA.
DR RefSeq; WP_011032470.1; NC_003901.1.
DR AlphaFoldDB; Q8PZH5; -.
DR GeneID; 82159527; -.
DR KEGG; mma:MM_0518; -.
DR PATRIC; fig|192952.21.peg.618; -.
DR eggNOG; arCOG02361; Archaea.
DR HOGENOM; CLU_000445_114_57_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AAM30214.1};
KW Transferase {ECO:0000313|EMBL:AAM30214.1}.
FT DOMAIN 329..374
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 376..428
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 425..495
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 498..550
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 551..621
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 623..675
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 683..901
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 534..561
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 901 AA; 102434 MW; 030709ABAA219406 CRC64;
MKTDLEQFPA KNPNPVLSVA NNCTVLYSNK AGEPLLHEWG VVVGEKLPSY LRDLVKSVIT
LNRPEKMELK IEKKVYLVAF HPSSEEKCVN IYGFDITDQK ELEERLRIKE KQNDILYRIG
KVALEFESLQ IFLDESVKLI ANILEVEYCK ILELMPDGNF LLRAGSGWKH GLVGKAIIGG
EKESQAGYTL FSGMPVVVED FAGESRFKKP EILRMHEVNS GVSVTIGSIG KIFGVLGVHS
RKKRKFTSDD TYFLSSVAFL IAQVIERKKA EEALKEAHDS LEETVTERTS ELEKSYISLK
ESESRLAEAQ RMAHIGSWDW NLITGEVCWS DELYHIFGRS PQESGATYDE FLSYVHPDDR
DRVDNALKKG LNGESVAGNY RIILGDGEER IVRTEAEVVF DEKNNPVQVK GTVQDITEIK
KVEEQLKILA NIVESSNDAI GTISLDGNIT GWNQEAENVY GYSVGEVLGK PVSIVTPPHL
DKETIKLIEE IMHGKKVQHY ETLRLRKDGT TIYVSITLSP VFDSYGKLIA ISFISRDITE
RKKIEEKLRE SEEKYRNIVE TANEGISIVD AEERITFVNK KIEDMFGYSS EELIGGSMWD
LLSDESKTII KQMLEKGWKN VNESFEIKFI HKDGYPVWTY TNSKSLFDKD GKFFGTMNLH
TDITKRKEAE EALRNFEIAR KKEIHHRIKN NLQVICSLLD LQAEKFRSRE SAEDTEVLNA
FIESQNRVMS IALIHEELHE GRGTDTLNFS PYLEKLVENL FQTYILENVN TSLDIKLEEN
IFFDMDTAIP LGIIVNELVS NSLKYAFSGR DYGEIQIKLY REDSAEHENK EQRVIKESYG
GTNVILIVSD NGIGIPEDFN LEDSSSLGLQ LVKILVDQLE GQIELNRDSG TEFTIRFTVQ
I
//
