ID   Q8QXK2_TUMVJ            Unreviewed;       499 AA.
AC   Q8QXK2;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Genome polyprotein {ECO:0000256|ARBA:ARBA00020107};
DE   Flags: Fragment;
OS   Turnip mosaic virus (strain Japanese) (TuMV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC   Patatavirales; Potyviridae; Potyvirus.
OX   NCBI_TaxID=12230 {ECO:0000313|EMBL:CAC85180.1};
OH   NCBI_TaxID=126270; Alliaria petiolata (Garlic mustard) (Arabis petiolata).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=38206; Calanthe.
OH   NCBI_TaxID=3719; Capsella bursa-pastoris (Shepherd's purse) (Thlaspi bursa-pastoris).
OH   NCBI_TaxID=264418; Hesperis matronalis.
OH   NCBI_TaxID=13274; Stellaria media (Common chickweed) (Alsine media).
OH   NCBI_TaxID=74517; Trifolium hybridum (Alsike clover).
RN   [1] {ECO:0000313|EMBL:CAC85180.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Xiaoshan R5 {ECO:0000313|EMBL:CAC85180.1};
RA   Chen J., Chen J.P., Adams M.J.;
RT   "Variation between Turnip mosaic virus isolates in Zhejiang province, China
RT   and evidence for recombination.";
RL   J. Phytopathol. 150:142-145(2002).
CC   -!- FUNCTION: Involved in aphid transmission, cell-to-cell and systemis
CC       movement, encapsidation of the viral RNA and in the regulation of viral
CC       RNA amplification. {ECO:0000256|ARBA:ARBA00029405}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000256|ARBA:ARBA00004328}.
CC   -!- SIMILARITY: Belongs to the potyviridae genome polyprotein family.
CC       {ECO:0000256|ARBA:ARBA00006064, ECO:0000256|RuleBase:RU003351}.
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DR   EMBL; AJ307039; CAC85180.1; -; Genomic_RNA.
DR   PIR; A48347; A48347.
DR   PIR; PQ0757; PQ0757.
DR   PIR; PQ0759; PQ0759.
DR   PIR; S21499; S21499.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001592; Poty_coat.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR   Pfam; PF00767; Poty_coat; 1.
DR   Pfam; PF00680; RdRP_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE   3: Inferred from homology;
KW   Capsid protein {ECO:0000313|EMBL:CAC85180.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953};
KW   Virion {ECO:0000256|ARBA:ARBA00022844}.
FT   DOMAIN          1..60
FT                   /note="RdRp catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50507"
FT   REGION          219..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        221..265
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAC85180.1"
SQ   SEQUENCE   499 AA;  57603 MW;  73F28CC790FB9E7F CRC64;
     GNNSGQPSTV VDNTLMVILA VNYSLRKSGI PNELRDSLIR FFVNGDDLLL GVHPKYEYVL
     DTMADNFREL GLKYTFDSRT REKGDLWFMS HQGHKREGVW IPKLEPERIV SILEWDRSKE
     PCHRLEAICA AMIESWGYDK LTHEIRKFYA WMIEQAPYSS LAQEGKAPYI AETALRKLYL
     DKEPAQEDLT QYLQAIFEDY EDGAEVCVYH QAGETLDAGL TEEQKQAEKE RKERERSEKE
     RERQRQLALK KGKNAAQEEG ERDNEVNAGT SGTFSVPRLK SLTSKMRVPK YEKRVALNLD
     HLILYTPEQT DLSNTRSTRK QFDTWFEGVM ADYELTEDKM QIILNGLMVW CIENGTSPNI
     NGMWVMMDGD DQVEFPIKPL IDHAKPTFRQ IMAHFSDVAE AYIEKRNQDR PYMPRYGLQR
     NLTDMSLARY AFDFYEMTSR TPIRAREAHI QMKAAALRGA NNNLFGLDGN VGTTVENTER
     HTTEDVNRNM HNLLGVKGL
//