ID   Q8RKG1_CLODI            Unreviewed;       361 AA.
AC   Q8RKG1;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Transposase-like protein B {ECO:0000313|EMBL:CAC81802.1};
GN   Name=tlpB {ECO:0000313|EMBL:CAC81802.1};
OS   Clostridioides difficile (Peptoclostridium difficile).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Clostridioides.
OX   NCBI_TaxID=1496 {ECO:0000313|EMBL:CAC81802.1};
RN   [1] {ECO:0000313|EMBL:CAC81802.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C34 {ECO:0000313|EMBL:CAC81802.1};
RA   Braun V., Mehlig M.;
RT   "A chimeric ribozyme in Clostridium difficile combines features of group I
RT   introns and insertion elements.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC       family. {ECO:0000256|ARBA:ARBA00008761}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC       family. {ECO:0000256|ARBA:ARBA00011044}.
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DR   EMBL; AJ269492; CAC81802.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8RKG1; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   InterPro; IPR010095; Cas12f1-like_TNB.
DR   InterPro; IPR001959; Transposase.
DR   InterPro; IPR021027; Transposase_put_HTH.
DR   NCBIfam; NF040570; guided_TnpB; 1.
DR   NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR   NCBIfam; NF038281; IS200_TnpB; 1.
DR   PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR   PANTHER; PTHR30405; TRANSPOSASE; 1.
DR   Pfam; PF12323; HTH_OrfB_IS605; 1.
DR   Pfam; PF01385; OrfB_IS605; 1.
DR   Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Transposition {ECO:0000256|ARBA:ARBA00022578};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          1..37
FT                   /note="Transposase putative helix-turn-helix"
FT                   /evidence="ECO:0000259|Pfam:PF12323"
FT   DOMAIN          156..268
FT                   /note="Probable transposase IS891/IS1136/IS1341"
FT                   /evidence="ECO:0000259|Pfam:PF01385"
FT   DOMAIN          280..350
FT                   /note="Cas12f1-like TNB"
FT                   /evidence="ECO:0000259|Pfam:PF07282"
SQ   SEQUENCE   361 AA;  42384 MW;  D4F8637F5AC62C80 CRC64;
     MYPNKKQQEL INKTFGCCRF VYNKYLAKRI EVYKNNKETF TYKQCSSDLT NLKKELKWLK
     EPDKFSLQNA LKDLDNAYKK FFKEKSGFPK FKSKKINRFS YKTNFTNGNI MYFSQHIKLP
     KLGMVKIRDK QVPQGRILNA TISKEPSGRY YVSLCCTDVD IEAFENTNNQ IGLDLGIKEF
     CISSCGDFIE NPKYLKKSLS KLAKLQRELS RKTIGSLNRN KARLKVARLQ EHIANQRNDF
     LQKLSTKLIK ENDIICIEDL QVKNMIRNRK LSRLISDVSW SEFIRQLKYK ANWHGRQIVK
     VGKFFASSQI CNKCGYKNEE MKDLNIREWI CPSCNETHDR DINASINILK EGLRLITIQN
     K
//