ID Q8RWE1_ARATH Unreviewed; 355 AA.
AC Q8RWE1;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 144.
DE SubName: Full=Metallo-beta-lactamase family protein {ECO:0000313|EMBL:AEE86243.1};
GN OrderedLocusNames=At4g33540 {ECO:0000313|EMBL:AEE86243.1};
GN ORFNames=T16L1.30 {ECO:0000313|EMBL:AEE86243.1}, T16L1_30
GN {ECO:0000313|EMBL:AEE86243.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAM13147.1};
RN [1] {ECO:0000313|EMBL:AEE86243.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=10617198; DOI=10.1038/47134;
RG EU;
RG CSHL and WU Arabidopsis Sequencing Project;
RA Mayer K., Schuller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Dusterhoft A., Stiekema W., Entian K.D., Terryn N., Harris B., Ansorge W.,
RA Brandt P., Grivell L., Rieger M., Weichselgartner M., de Simone V.,
RA Obermaier B., Mache R., Muller M., Kreis M., Delseny M., Puigdomenech P.,
RA Watson M., Schmidtheini T., Reichert B., Portatelle D., Perez-Alonso M.,
RA Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H.,
RA Ridley P., Langham S.A., McCullagh B., Bilham L., Robben J.,
RA Van der Schueren J., Grymonprez B., Chuang Y.J., Vandenbussche F.,
RA Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
RA Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E.,
RA Brandt A., Peters S., van Staveren M., Dirske W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Kotter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., Van Montagu M., Rogers J.,
RA Cronin A., Quail M., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M.,
RA Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M.,
RA Benes V., Rechmann S., Borkova D., Blocker H., Scharfe M., Grimm M.,
RA Lohnert T.H., Dose S., de Haan M., Maarse A., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
RA Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O.,
RA Quigley F., Clabauld G., Mundlein A., Felber R., Schnabl S., Hiller R.,
RA Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C.,
RA Montfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sehkon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L., Nelson J.,
RA Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J.,
RA Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffmann J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2] {ECO:0000313|EMBL:AAM13147.1}
RP NUCLEOTIDE SEQUENCE.
RA Southwick A., Karlin-Neumann G., Nguyen M., Lam B., Miranda M., Palm C.J.,
RA Bowser L., Jones T., Banh J., Carninci P., Chen H., Cheuk R., Chung M.K.,
RA Hayashizaki Y., Ishida J., Kamiya A., Kawai J., Kim C., Lin J., Liu S.X.,
RA Narusaka M., Pham P.K., Sakano H., Sakurai T., Satou M., Seki M., Shinn P.,
RA Yamada K., Shinozaki K., Ecker J., Theologis A., Davis R.W.;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAO30054.1}
RP NUCLEOTIDE SEQUENCE.
RA Southwick A., Nguyen M., Tripp M., Palm C.J., Jones T., Wu T., Carninci P.,
RA Chen H., Cheuk R., Chan M.M., Chang C.H., Dale J.M., Deng J.M.,
RA Hayashizaki Y., Hsuan V.W., Lee J.M., Ishida J., Kamiya A., Kawai J.,
RA Kim C.J., Narusaka M., Onodera C.S., Quach H.L., Sakurai T., Satou M.,
RA Seki M., Shinn P., Tang C.C., Toroumi M., Wong C., Wu H.C., Yamada K.,
RA Yu G., Yuan S., Shinozaki K., Ecker J., Theologis A., Davis R.W.;
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:BAE98442.1}
RP NUCLEOTIDE SEQUENCE.
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Morosawa T.,
RA Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K.,
RA Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K.,
RA Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
RA Hayashizaki Y., Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AEE86243.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AEE86243.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; AY093148; AAM13147.1; -; mRNA.
DR EMBL; BT003391; AAO30054.1; -; mRNA.
DR EMBL; CP002687; AEE86243.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66862.1; -; Genomic_DNA.
DR EMBL; AK226283; BAE98442.1; -; mRNA.
DR RefSeq; NP_001328731.1; NM_001342220.1.
DR RefSeq; NP_195080.2; NM_119509.5.
DR AlphaFoldDB; Q8RWE1; -.
DR SMR; Q8RWE1; -.
DR STRING; 3702.Q8RWE1; -.
DR PaxDb; 3702-AT4G33540-1; -.
DR ProteomicsDB; 181583; -.
DR EnsemblPlants; AT4G33540.1; AT4G33540.1; AT4G33540.
DR EnsemblPlants; AT4G33540.2; AT4G33540.2; AT4G33540.
DR GeneID; 829493; -.
DR Gramene; AT4G33540.1; AT4G33540.1; AT4G33540.
DR Gramene; AT4G33540.2; AT4G33540.2; AT4G33540.
DR KEGG; ath:AT4G33540; -.
DR TAIR; AT4G33540; -.
DR eggNOG; ENOG502QPS3; Eukaryota.
DR HOGENOM; CLU_056853_1_0_1; -.
DR OrthoDB; 1250at2759; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8RWE1; baseline and differential.
DR GO; GO:0019904; F:protein domain specific binding; IPI:CAFA.
DR GO; GO:0046685; P:response to arsenic-containing substance; IEP:TAIR.
DR CDD; cd07727; YmaE-like_MBL-fold; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR42773:SF1; METALLO-BETA-LACTAMASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR42773; METALLO-BETA-LACTAMASE-RELATED; 1.
DR Pfam; PF13370; Fer4_13; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q8RWE1,
KW ECO:0007829|ProteomicsDB:Q8RWE1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 160..318
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 355 AA; 39638 MW; 42B3469E970BDDD5 CRC64;
MASASFSAVS SLSYQFRSKE AIFSSKASCF SSTALSGRRV FGSIKAAQVT SHENPRRRTQ
NVEGDIFVDN TCIDCDTCRW MVPDLFTRVD NMSAVTKQPT CKEERLNALQ ALLSCPTGSI
RTQTPPADIG EAQETFPLVV DKDTLPGVFH CGFHSKKSYG ATSYLILHRE GNILVDSPRY
VEKLAGKIEM KGGVRYMFLT HRDDVADHKK WADRFKSTRI LHSDDVEPST SDVELKLEGS
GPWSIYEDVE LIHTPGHSEG SVCMFHKSLK ALFTGDHVIM TESGLSILEQ YNHGSVPLQL
ENVEKLINLD FNWLIPGHGR RVHFKDGDEK AKNLEALVQK HREKQLVSFS KSGKA
//
