ID Q8T4T5_AEDAE Unreviewed; 268 AA.
AC Q8T4T5;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Chymotrypsin-like protein {ECO:0000313|EMBL:AAL85583.1};
GN Name=CHYM {ECO:0000313|EMBL:AAL85583.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:AAL85583.1};
RN [1] {ECO:0000313|EMBL:AAL85583.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MOYO-R {ECO:0000313|EMBL:AAL85583.1};
RA Morlais I., Severson D.W.;
RT "Single nucleotide polymorphism and codon usage bias in Aedes aegypti.";
RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC {ECO:0000256|ARBA:ARBA00024195}.
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DR EMBL; AY064082; AAL85583.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8T4T5; -.
DR VEuPathDB; VectorBase:AAEL003060; -.
DR HOGENOM; CLU_006842_7_0_1; -.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24250; CHYMOTRYPSIN-RELATED; 1.
DR PANTHER; PTHR24250:SF65; PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..268
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004314291"
FT DOMAIN 26..267
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 268 AA; 29018 MW; 68F4886C732C732E CRC64;
MAFKLTVAFL LVASLALASS RATHKIVGGD EAEAHEFPYQ ISLQWNFNDG QTETMHFCGA
SVLNENFVLT AAHCKTAYSN TGFIEVVADE HDVAVAEGSE QRRLVAEFIV HEDYQGGVSP
DDIAVIRVDK PFELNDKVKA VKLPKQLEQF EGDVTLSGWG SVSTTVFPDY PDKLRKVVLP
LVDYEQCNAL WDNDSALAKS NVCAGPIDGS KSACSADSGG PLVKQSGEDV IQVGVVSWGA
VPCGSPRRPT VFAGVSHYVD WIEQQLRA
//
