ID Q8TH74_METAC Unreviewed; 264 AA.
AC Q8TH74;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN OrderedLocusNames=MA_4648 {ECO:0000313|EMBL:AAM07982.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM07982.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM07982.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
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DR EMBL; AE010299; AAM07982.1; -; Genomic_DNA.
DR RefSeq; WP_011024516.1; NC_003552.1.
DR AlphaFoldDB; Q8TH74; -.
DR STRING; 188937.MA_4648; -.
DR EnsemblBacteria; AAM07982; AAM07982; MA_4648.
DR GeneID; 1476542; -.
DR KEGG; mac:MA_4648; -.
DR HOGENOM; CLU_076812_4_0_2; -.
DR InParanoid; Q8TH74; -.
DR OrthoDB; 8919at2157; -.
DR PhylomeDB; Q8TH74; -.
DR Proteomes; UP000002487; Chromosome.
DR CDD; cd02205; CBS_pair_SF; 3.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR PANTHER; PTHR43080; CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43080:SF2; CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL; 1.
DR Pfam; PF00571; CBS; 4.
DR SMART; SM00116; CBS; 4.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487}.
FT DOMAIN 7..65
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 68..127
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 134..193
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 208..264
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 264 AA; 29401 MW; 135976D551D7B4F4 CRC64;
MNVSEIMSEG PVSIKERDFV THARQLMRDY LFRSLVVVDE GNRLVGMLND QDIMRVTSTR
SNVTVGGYAR PSPTVTPDMD VVKAAKLMVQ SKQNRVPVVK STTDHTVVGV LSDVDILRNA
ELPRSASKTI DMVMTKKVKT CSPDERISKV WNYMTETDYT GIPVVSKKGD PIGMITRRDI
IKAGILRMSI EDERAARPNE SPKVEKIMST PAYTLSENDS VKSAIEMIIQ HDIGRVTIVN
EQGKISGIAD RQDLMNAFVN GWSE
//
