ID Q8TPW0_METAC Unreviewed; 481 AA.
AC Q8TPW0;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Metallo-beta-lactamase {ECO:0000313|EMBL:AAM05200.1};
GN OrderedLocusNames=MA_1794 {ECO:0000313|EMBL:AAM05200.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM05200.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM05200.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
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DR EMBL; AE010299; AAM05200.1; -; Genomic_DNA.
DR RefSeq; WP_011021797.1; NC_003552.1.
DR AlphaFoldDB; Q8TPW0; -.
DR SMR; Q8TPW0; -.
DR STRING; 188937.MA_1794; -.
DR EnsemblBacteria; AAM05200; AAM05200; MA_1794.
DR GeneID; 1473683; -.
DR KEGG; mac:MA_1794; -.
DR HOGENOM; CLU_030571_7_1_2; -.
DR InParanoid; Q8TPW0; -.
DR OrthoDB; 9180at2157; -.
DR PhylomeDB; Q8TPW0; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050313; F:sulfur dioxygenase activity; IBA:GO_Central.
DR GO; GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR GO; GO:0070813; P:hydrogen sulfide metabolic process; IBA:GO_Central.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd07724; POD-like_MBL-fold; 1.
DR CDD; cd00158; RHOD; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 2.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR044528; POD-like_MBL-fold.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43084; PERSULFIDE DIOXYGENASE ETHE1; 1.
DR PANTHER; PTHR43084:SF1; PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF00581; Rhodanese; 2.
DR SMART; SM00849; Lactamase_B; 1.
DR SMART; SM00450; RHOD; 2.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 2.
DR PROSITE; PS50206; RHODANESE_3; 2.
PE 4: Predicted;
KW ATP synthesis {ECO:0000256|ARBA:ARBA00023310};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781};
KW Ion transport {ECO:0000256|ARBA:ARBA00022781};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487};
KW Transport {ECO:0000256|ARBA:ARBA00022781}.
FT DOMAIN 264..355
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 370..458
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 481 AA; 53224 MW; F771E144BFBFCC9C CRC64;
MQIIPFFVRG IAHSSYILAG KKSCAIIDPQ RDVEIYIREA KSRGLKITHI LETHLHADFV
SGHMDLAELT GAPIYAPEAA KCEFEHVGLV EGDTFEIEDM TVKVLETPGH TPEHISYVVS
DTSRGPDPTA VFCGDTLFVG DVGRPDLFPG KARELASTLY DSLHKKLLSL PDSCEVYPAH
GEGSLCGRAM GAKRSSTIGY ERKYNYALQI PDREGFIENL TTDMPPAPYH FSRCSEINRK
GPTKLREIPP PKELPPGEFF RFAGRDNTEV LDSRHYDNFG GEHVPGAWCI DLRSNFATYA
GWLLPPERQI LLVSDSEKDA RESAVWLHRV GLDRIAGFLS GEMFAWATAG LRASHVSQVS
IPELYEWVRS KNPPLILDVR ASSEYESFHI ENALNIQVQD LRKRYRELDP EAEYAVICST
GQRSGIGCSI LKKHGFSRVN NAAGGMTGYN AAGFGPECPM CALSWAGKAG KKEVVPIQKG
K
//
