ID Q8U364_PYRFU Unreviewed; 375 AA.
AC Q8U364;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:AAL80732.1};
GN OrderedLocusNames=PF0608 {ECO:0000313|EMBL:AAL80732.1};
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497 {ECO:0000313|EMBL:AAL80732.1, ECO:0000313|Proteomes:UP000001013};
RN [1] {ECO:0000313|EMBL:AAL80732.1, ECO:0000313|Proteomes:UP000001013}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1
RC {ECO:0000313|Proteomes:UP000001013};
RX PubMed=10430560;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
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DR EMBL; AE009950; AAL80732.1; -; Genomic_DNA.
DR RefSeq; WP_011011728.1; NZ_CP023154.1.
DR AlphaFoldDB; Q8U364; -.
DR STRING; 186497.PF0608; -.
DR PaxDb; 186497-PF0608; -.
DR GeneID; 41712413; -.
DR KEGG; pfu:PF0608; -.
DR PATRIC; fig|186497.12.peg.639; -.
DR eggNOG; arCOG00984; Archaea.
DR HOGENOM; CLU_007207_0_0_2; -.
DR OrthoDB; 57329at2157; -.
DR PhylomeDB; Q8U364; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001013}.
FT DOMAIN 6..364
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 375 AA; 41375 MW; 9E0348653AEDCBC8 CRC64;
MFFLKTKIIE GRGSLEYLQK EAIGFERALI LASSSMKRLG FLKEAEDYLR EGGVEVISIA
GLPPEPTKDV VDEFLPKVRE FSPEILIAIG GGSVIDMAKA LKVFYDVPGI SFEEVAIKSR
FSKPRPVPKL KTPLIAIPST SGAGSEVSAA SVIKVGDVKY TIVTPEIAPE VAILDPRLPE
GMPPEVARNS GMDVLVHAIE AYVSKASSPF TDAMAVKAAK AVLEHLEESI RGDKNAREKI
HYAATMAGIA FLNARLGLVH AMSHKAAWIG PHGLVNAILL PYVMEYNMAR RREKYDALAR
ELGFDNAEEL LEEIKALNER LGIGPISSYV SEEEFLAKLD EMVERAYEDP LVNFNPVEPR
KEDIRRIYER AFYGD
//
