ID Q8W2C0_SOYBN Unreviewed; 1124 AA.
AC Q8W2C0;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Functional candidate resistance protein KR1 {ECO:0000313|EMBL:AAL56987.1};
GN Name=KR1 {ECO:0000313|EMBL:AAL56987.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:AAL56987.1};
RN [1] {ECO:0000313|EMBL:AAL56987.1}
RP NUCLEOTIDE SEQUENCE.
RA He C., Chen S.;
RL Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAL56987.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12647051;
RA He C.Y., Tian A.G., Zhang J.S., Zhang Z.Y., Gai J.Y., Chen S.Y.;
RT "Isolation and characterization of a full-length resistance gene homolog
RT from soybean.";
RL Theor. Appl. Genet. 106:786-793(2003).
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DR EMBL; AF327903; AAL56987.1; -; mRNA.
DR RefSeq; NP_001237766.1; NM_001250837.1.
DR AlphaFoldDB; Q8W2C0; -.
DR GeneID; 548035; -.
DR KEGG; gmx:548035; -.
DR OrthoDB; 887689at2759; -.
DR ExpressionAtlas; Q8W2C0; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF219; ARCHAEAL ATPASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1101..1119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..185
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1124 AA; 128675 MW; 3ACA10F562FC7C2C CRC64;
MAKQSSSSSF SYRFSNDVFL SFRGEDTRRG FTGNLYKALS DRGIHTFMDD KKIPRGDQIT
SGLEKAIEES RIFIIVLSEN YASSSFCLNE LDYILKFIKG KGILILPVFY KVDPSDVRNH
TGSFGKALTN HEKKFKSTND MEKLETWKMA LNKVANLSGY HHFKHGEEYE YEFIQRIVEL
VSKKINRAPL HVADYPVGLE SRIQEVKALL DVGSDDVVHM LGIHGLGGVG KTTLAAAVYN
SIADHFEALC FLQNVRETSK KHGLQHLQRN LLSEMAGEDK LIGVKQGISI IEHRLRQKKV
LLILDDVDKR EQLQALAGRP DLFGPGSRVI ITTRDKQLLA CHGVERTYEV NELNEEYALE
LLNWKAFKLE KVDPFYKDVL NRAATYASGL PLALEVIGSN LSGKNIEQWI SALDRYKRIP
NKEIQEILKV SYDALEEDEQ SIFLDIACCF KKYDLAEVQD ILHAHHGHCM KHHIGVLVEK
SLIKISLDGY VTLHDLIEDM GKEIVRKESP QEPGKRSRLW LPTDIVQVLE ENKGTSHIGI
ICMNFYSSFE EVEIQWDGDA FKKMKNLKTL IIRSGHFSKG PKHFPKSLRV LEWWRYPSHY
FPYDFQMEKL AIFNLPDCGF TSRELAAMLK KKFVNLTSLN FDSCQHLTLI PDVSCVPHLQ
KLSFKDCDNL YAIHPSVGFL EKLRILDAEG CSRLKNFPPI KLTSLEQLKL GFCHSLENFP
EILGKMENIT ELDLEQTPVK KFPLSFQNLT RLETVLLCFP RNQANGCTGI FLSNICPMQE
SPELINVIGV GWEGCLFRKE DEGAENVSLT TSSNVQFLDL RNCNLSDDFF PIALPCFANV
MELNLSGNNF TVIPECIKEC RFLTTLYLNY CERLREIRGI PPNLKYFYAE ECLSLTSSCR
SMLLSQELHE AGRTFFYLPG AKIPEWFDFQ TSEFPISFWF RNKFPAIAIC HIIKRVAEFS
SSRGWTFRPN IRTKVIINGN ANLFNSVVLG SDCTCLFDLR GERVTDNLDE ALLENEWNHA
EVTCPGFTFT FAPTFIKTGL HVLKQESNME DIRFSDPCRK TKLDNDFNSS KPKNQRWVGN
DVAKTQVVQQ QQLMGSFLSR MWHWALVFLI SFLVFLISCR RNNQ
//
