ID   Q8X7V7_ECO57            Unreviewed;       923 AA.
AC   Q8X7V7; A0A0H3JDE4; A0A0X8REB0; Q7AHJ3;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 162.
DE   SubName: Full=ATP-dependent Clp proteinase {ECO:0000313|EMBL:BAB33646.1};
GN   ORFNames=ECs_0223 {ECO:0000313|EMBL:BAB33646.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|EMBL:BAB33646.1, ECO:0000313|Proteomes:UP000000558};
RN   [1] {ECO:0000313|EMBL:BAB33646.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558};
RX   PubMed=11258796; DOI=.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC       {ECO:0000256|RuleBase:RU004432}.
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DR   EMBL; BA000007; BAB33646.1; -; Genomic_DNA.
DR   RefSeq; NP_308250.1; NC_002695.1.
DR   RefSeq; WP_000614374.1; NZ_SEKL01000021.1.
DR   AlphaFoldDB; Q8X7V7; -.
DR   SMR; Q8X7V7; -.
DR   STRING; 155864.Z0254; -.
DR   GeneID; 914094; -.
DR   KEGG; ecs:ECs_0223; -.
DR   PATRIC; fig|386585.9.peg.324; -.
DR   eggNOG; COG0542; Bacteria.
DR   HOGENOM; CLU_005070_2_1_6; -.
DR   OMA; CKNVVFF; -.
DR   Proteomes; UP000000558; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 4.10.860.10; UVR domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR017729; ATPase_T6SS_ClpV1.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03345; VI_ClpV1; 1.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF182; CLP ATPASE; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF81923; Double Clp-N motif; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004432};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000558}.
FT   DOMAIN          217..362
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          647..795
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          813..905
FT                   /note="Clp ATPase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01086"
FT   REGION          508..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   923 AA;  101230 MW;  0D1465A573031035 CRC64;
     MIQIDLPTLV KRLNLFSRQA LEMAASECMS QQAAEITVSH VLIQMLAMPR SDLRVITRQG
     DIGMEELRQA LTVENYTTAR SADSYPAFSP MLVEWLKEGW LLASAEMQHS ELRGGVLLLA
     LLHSPLRYIP PAAARLLTGI NRDRLQQDFV QWTQESAESV VPDADGKGAG TLTDASDTLL
     ARYAKNMTED ARNGRLAPVL CRDHEIDLMI DILCRRRKNN PVVVGEAGVG KSALIEGLAL
     RIVAGQVPDK LKNTDIMTLD LGALQAGASV KGEFEKRFKG LMAEVISSPV PVILFIDEAH
     TLIGAGNQQG GLDISNLLKP ALARGELKTI AATTWSEYKK YFEKDAALSR RFQLVKVSEP
     NAAEATIILR GLSAVYERSH GVLIDDDALQ AAATLSERYL SGRQLPDKAI DVLDTACARV
     AINLSSPPKQ ISALTTLSHQ QEAEIRQLER ELRIGLRTDT SRMTEVLVQY DETLTALDEL
     EAAWHQQQTL VREIIALRQQ LLGVAEDDAA PLPDADTVED TQPESESESE QDNTGAVPAD
     ETDREQPEET AETVSPVQRL AQLTAELDAL HNDRLLVSPH VDKKQIAAVI AEWTGVPLNR
     LSQNEMSVIT DLPKWLGDTI KGQDLAIASL HKHLLTARAD LRRPGRPLGA FLLAGPSGVG
     KTETVLQLAE LLYGGRQYLT TINMSEFQEK HTVSRLIGSP PGYVGYGEGG VLTEAIRQKP
     YSVVLLDEVE KAHPDVLNLF YQAFDKGEMA DGEGRLIDCK NIVFFLTSNL GYQVIVEHAD
     DPETMQEALY PVLADFFKPA LLARMEVVPY LPLSKETLAT IIAGKLARLD NVLRSRFGAE
     VVIEPEVTDE IMSRVTRAEN GARMLESVID GDMLPPLSLL LLQKMAANTA IARIRLSAVD
     GAFTADVEDA QNDESVTKDE TVL
//