UniProt: Q8XEX2

Database: UniProt
Entry: Q8XEX2_SALTI

LinkDB:  Q8XEX2_SALTI 
Original site:  Q8XEX2_SALTI

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Ontology (1)   
   GO (1)   
Gene (2)   
   KEGG GENES (2)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (3)   
   EMBL (3)   
Protein domain (5)   
   InterPro (3)   
   Pfam (2)   
Literature (3)   
   PubMed (3)   
All databases (16)   

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ID   Q8XEX2_SALTI            Unreviewed;       287 AA.
AC   Q8XEX2; A0A0B4P213; A0A0C9E1A4; Q7ALY6;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 132.
DE   SubName: Full=YicC family protein {ECO:0000313|EMBL:HAE0415142.1};
GN   OrderedLocusNames=STY4059 {ECO:0000313|EMBL:CAD03258.1}, t3783
GN   {ECO:0000313|EMBL:AAO71265.1};
GN   ORFNames=G2244_00410 {ECO:0000313|EMBL:HAE0415142.1};
OS   Salmonella typhi.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370 {ECO:0000313|EMBL:CAD03258.1, ECO:0000313|Proteomes:UP000000541};
RN   [1] {ECO:0000313|EMBL:CAD03258.1, ECO:0000313|Proteomes:UP000000541}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18 {ECO:0000313|EMBL:CAD03258.1,
RC   ECO:0000313|Proteomes:UP000000541};
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.,
RA   Rutherford K., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2] {ECO:0000313|EMBL:AAO71265.1, ECO:0000313|Proteomes:UP000002670}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2 {ECO:0000313|Proteomes:UP000002670}, and Ty2
RC   {ECO:0000313|EMBL:AAO71265.1};
RX   PubMed=12644504; DOI=10.1128/JB.185.7.2330-2337.2003;
RA   Deng W., Liou S.R., Plunkett G.III., Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
RN   [3] {ECO:0000313|EMBL:HAE0415142.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sam_1c96eabc-5ba9-4785-8bb4-b62bc64a6574
RC   {ECO:0000313|EMBL:HAE0415142.1};
RX   PubMed=30286803;
RA   Souvorov A., Agarwala R., Lipman D.J.;
RT   "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL   Genome Biol. 19:153-153(2018).
RN   [4] {ECO:0000313|EMBL:HAE0415142.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sam_1c96eabc-5ba9-4785-8bb4-b62bc64a6574
RC   {ECO:0000313|EMBL:HAE0415142.1};
RG   NCBI Pathogen Detection Project;
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|ARBA:ARBA00001968};
CC   -!- SIMILARITY: Belongs to the YicC/YloC family.
CC       {ECO:0000256|ARBA:ARBA00035648}.
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DR   EMBL; AE014613; AAO71265.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD03258.1; -; Genomic_DNA.
DR   EMBL; DAAQQG010000001; HAE0415142.1; -; Genomic_DNA.
DR   RefSeq; NP_458191.1; NC_003198.1.
DR   RefSeq; WP_000621352.1; NZ_WSUR01000001.1.
DR   SMR; Q8XEX2; -.
DR   STRING; 220341.gene:17587902; -.
DR   DNASU; 1250289; -.
DR   KEGG; stt:t3783; -.
DR   KEGG; sty:STY4059; -.
DR   PATRIC; fig|220341.7.peg.4144; -.
DR   eggNOG; COG1561; Bacteria.
DR   HOGENOM; CLU_076609_0_0_6; -.
DR   OMA; INREVNT; -.
DR   OrthoDB; 9771229at2; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR   InterPro; IPR013551; YicC-like_C.
DR   InterPro; IPR013527; YicC-like_N.
DR   InterPro; IPR005229; YicC/YloC-like.
DR   NCBIfam; TIGR00255; YicC/YloC family endoribonuclease; 1.
DR   PANTHER; PTHR30636; UNCHARACTERIZED; 1.
DR   PANTHER; PTHR30636:SF3; UPF0701 PROTEIN YICC; 1.
DR   Pfam; PF08340; DUF1732; 1.
DR   Pfam; PF03755; YicC_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT   DOMAIN          2..153
FT                   /note="Endoribonuclease YicC-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03755"
FT   DOMAIN          203..287
FT                   /note="Endoribonuclease YicC-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08340"
FT   COILED          182..218
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   287 AA;  33125 MW;  E3928348CF7F1CF7 CRC64;
     MIRSMTAYAR REIKGEWGSA TWEMRSVNQR YLETYFRLPE QFRSLEPVVR ERIRTRLTRG
     KVECMLRFEP DASAQGELIL NEKLAKQLVS AANWVKMQSD EGEINPVDIL RWPGVMAAQE
     QDLDAIAAEI LAALDGTLDD FIVARETEGQ ALKALIEQRL EGVSAEVAKV RAHMPEILQW
     QRERLVAKLE DAQVQLENNR LEQELVMMAQ RIDVAEELDR LEAHVKETYN ILKKKEAVGR
     RLDFMMQEFN RESNTLASKS INADVTNSAI ELKVLIEQMR EQIQNIE
//

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