ID   Q8XMX4_CLOPE            Unreviewed;       728 AA.
AC   Q8XMX4;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=Stage V sporulation protein D {ECO:0000313|EMBL:BAB80270.1};
GN   Name=spoVD {ECO:0000313|EMBL:BAB80270.1};
OS   Clostridium perfringens (strain 13 / Type A).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195102 {ECO:0000313|EMBL:BAB80270.1, ECO:0000313|Proteomes:UP000000818};
RN   [1] {ECO:0000313|EMBL:BAB80270.1, ECO:0000313|Proteomes:UP000000818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13 / Type A {ECO:0000313|Proteomes:UP000000818};
RX   PubMed=11792842; DOI=10.1073/pnas.022493799;
RA   Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA   Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT   "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT   eater.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; BA000016; BAB80270.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8XMX4; -.
DR   SMR; Q8XMX4; -.
DR   STRING; 195102.gene:10489821; -.
DR   KEGG; cpe:CPE0564; -.
DR   HOGENOM; CLU_009289_6_0_9; -.
DR   Proteomes; UP000000818; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR   CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   InterPro; IPR011927; SpoVD_pbp.
DR   NCBIfam; TIGR02214; spoVD_pbp; 1.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 2.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR   PROSITE; PS51178; PASTA; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000818};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          604..664
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
FT   DOMAIN          668..728
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   728 AA;  79690 MW;  131353AE9B8E9418 CRC64;
     MKRSYRDMAI IRKRLSFILA FIIIMCFILS IRLSYVMIVK GPEYAELAVE QWTNEVKISA
     RRGKILDRDL NELAVSSNVY RVDFNLNAIR SYTKKTGKTN EELALEISKV LEMDKDTVLK
     KLEFKLPSGA PAGAAILARR IEKEKADKVK ELEIPGVMVS PDTQRYYPND NFLSHVLGTT
     NSDGVGLNGI ELKYDRVLSG SPGLKITEMV KDGAEYPYTI SRFTAPVDGK DVVLTIDEKL
     QYFAEQIAEI GLIHHNADAA SVIIMNPNNG EILAMSNKPD FNPNKPYDGA ENFSGNTSSD
     RIQKMWRNRS VSDSFEPGSI FKIITASAAV QEGVAGKDET YTCSGGLQKG DRFIKCWKRG
     GHGTQTFEEI IQNSCNVGFM NLGEKLGAEK LNEYIKKFGL GKKSGVDLPG ESPGIVKKTE
     NITDMDLATI SFGQTNTVNP IQFMTAVNAV ANGGTLIQPH VVKEISYINE NNDRVIDETF
     VPKKTENLIS KETADQIKLA LENAVKNGSA KGAYKEGYGV AGKTGTAQKV NPETGGYGGG
     YVASFVGFAP YDNPQISVMV SVDNPKNGEY YGGRVAAPLA GMLLQNIFNY IDLTEFHLDE
     KLPEKETVII PEVRGLPIND TTSMLKELGI SYEIEGEGEF IVESNPAPGY PISPDTKITL
     IAGDSSNLNS DVIIPDFKNY SKESAEKLLN QLGLIGEFVG EGPSVTKQSI SPDEVVNGNS
     KITLTLGY
//