ID   Q8YC77_BRUME            Unreviewed;       729 AA.
AC   Q8YC77; D0B751;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:AAL53897.1};
DE            EC=3.1.3.1 {ECO:0000313|EMBL:AAL53897.1};
GN   OrderedLocusNames=BMEII0655 {ECO:0000313|EMBL:AAL53897.1};
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914 {ECO:0000313|EMBL:AAL53897.1, ECO:0000313|Proteomes:UP000000419};
RN   [1] {ECO:0000313|EMBL:AAL53897.1, ECO:0000313|Proteomes:UP000000419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094
RC   {ECO:0000313|Proteomes:UP000000419};
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.J.,
RA   Haselkorn R., Kyrpides N., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE008918; AAL53897.1; -; Genomic_DNA.
DR   PIR; AF3591; AF3591.
DR   RefSeq; WP_004681912.1; NZ_GG703779.1.
DR   AlphaFoldDB; Q8YC77; -.
DR   GeneID; 29595219; -.
DR   KEGG; bme:BMEII0655; -.
DR   KEGG; bmel:DK63_2590; -.
DR   PATRIC; fig|224914.52.peg.2716; -.
DR   eggNOG; COG4222; Bacteria.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR027372; Phytase-like_dom.
DR   InterPro; IPR011044; Quino_amine_DH_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR46928; MESENCHYME-SPECIFIC CELL SURFACE GLYCOPROTEIN; 1.
DR   PANTHER; PTHR46928:SF1; MESENCHYME-SPECIFIC CELL SURFACE GLYCOPROTEIN; 1.
DR   Pfam; PF13449; Phytase-like; 1.
DR   SUPFAM; SSF101898; NHL repeat; 1.
DR   SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AAL53897.1};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
SQ   SEQUENCE   729 AA;  78104 MW;  21F7888632E30CDE CRC64;
     MSKRSLTFAL LTALSASVAF SASAEPVFNR IASFAVAENL PEGADSSKPT SSEIITVSED
     GKTLIYSDSP YGAIGFIDIT GPAAPKAGGL LKVEGEPTSV VVAGPRVFAG VNTSESYKNP
     SGRLDVIDIA SRKVEQSCDL GGQPDSVATS PDRKFLAVAI ENERDEEFNN GELPQMPGGN
     LKIIELKDGK PDCAAMKTVD LTGIAEIAPE DPEPEFVAFN GKNEIAVTLQ ENNHIAIVDA
     ASGKILSHFS AGSVDLDKID TKKDGQIKFN GEMKGVNREP DSVKWLDDDR IVIANEGDYK
     GGSRGFSIFS KDGKLLHESG NTLEHRIARA GHYPEKRNKK GVEIEGAEAA IFGDTHYIFA
     ASERGSVVGV YKDTGKEPEF LQLLPSGIGP EGLLAIPSRK LFVTANETDL VKDGGARSHV
     MIYELQDKPA AYPQIVSNLA EDGTPIGWGA LSGLVADPQK DGIFYAVSDS AYYAAPTIYT
     IDANTKPAKI TAALLVKRGK DAAQKLDLEG ITTDGEGGFW LANEGNQAKL VPHAILNVDE
     KGVIRKEVAL PADLLKQQTR FGLEGITRLG EGDDAVLWMT VQREWADDDK GQVKLLAYSP
     KDESWKAVAY PLDAKEKGWV GLSEITAHDG NLYIIERDNL IGTEAVNKRL YKVALDGLKP
     VAIGAKLPVV KKTLVHDFIP DLKKLNGFVP DKLEGFAITR TGNAYAVTDN DGVDGSSGET
     QFFSIGKID
//