ID   Q8YJ16_BRUME            Unreviewed;       304 AA.
AC   Q8YJ16; D0BA23;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   SubName: Full=Geranyltranstransferase {ECO:0000313|EMBL:AAL51452.1};
DE            EC=2.5.1.10 {ECO:0000313|EMBL:AAL51452.1};
GN   OrderedLocusNames=BMEI0270 {ECO:0000313|EMBL:AAL51452.1};
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914 {ECO:0000313|EMBL:AAL51452.1, ECO:0000313|Proteomes:UP000000419};
RN   [1] {ECO:0000313|EMBL:AAL51452.1, ECO:0000313|Proteomes:UP000000419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094
RC   {ECO:0000313|Proteomes:UP000000419};
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.J.,
RA   Haselkorn R., Kyrpides N., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|RuleBase:RU004466}.
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DR   EMBL; AE008917; AAL51452.1; -; Genomic_DNA.
DR   PIR; AI3285; AI3285.
DR   RefSeq; WP_002964858.1; NZ_GG703781.1.
DR   AlphaFoldDB; Q8YJ16; -.
DR   GeneID; 58775228; -.
DR   KEGG; bme:BMEI0270; -.
DR   KEGG; bmel:DK63_1162; -.
DR   PATRIC; fig|224914.52.peg.1229; -.
DR   eggNOG; COG0142; Bacteria.
DR   Proteomes; UP000000419; Chromosome I.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:AAL51452.1}.
SQ   SEQUENCE   304 AA;  32315 MW;  2268FC9F21673E32 CRC64;
     MEKLPVDFTT LLNRRAMEVE AALAGLLDER PRTGEIARPQ RLIAAMRHGV LNGGKRLRPF
     LVLESAALFG QYGQAVLRVA AALECIHCYS LVHDDLPAMD DDDLRRGQPT VHKAFDEAAA
     ILAGDSLLTY AFDIIASDET ELDATTRIKL VCALTRASGL GGMAGGQALD LMAETRKPDE
     AGIITLQAMK TGALIRFACE AGAIIAGASQ EDRERMAEFG SAIGLAFQLA DDLLDVTADA
     GTMGKATGKD AAAGKATLVS LHGIDWTRQQ LSGLVAQAES LLAPFGEDAE PLKQAARFIA
     ERQN
//