ID Q8Z1V7_SALTI Unreviewed; 274 AA.
AC Q8Z1V7; A0A0C9ELL1; Q7C5Q4;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 24-JAN-2024, entry version 151.
DE SubName: Full=Acetate operon repressor {ECO:0000313|EMBL:CAD09192.1};
DE SubName: Full=Acetate operon transcriptional repressor IclR {ECO:0000313|EMBL:EBS0138743.1};
DE SubName: Full=Glyoxylate bypass operon transcriptional repressor IclR {ECO:0000313|EMBL:EBG5395265.1};
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:EDH5802516.1};
GN Name=iclR {ECO:0000313|EMBL:CAD09192.1};
GN OrderedLocusNames=STY4404 {ECO:0000313|EMBL:CAD09192.1}, t4114
GN {ECO:0000313|EMBL:AAO71578.1};
GN ORFNames=CAJ76_15330 {ECO:0000313|EMBL:EDG8858206.1}, CAJ80_13515
GN {ECO:0000313|EMBL:EDG8902423.1}, CAJ85_17650
GN {ECO:0000313|EMBL:EDG8894195.1}, CAL67_07010
GN {ECO:0000313|EMBL:EDG8932456.1}, CB224_18195
GN {ECO:0000313|EMBL:EDH5802516.1}, CC884_16440
GN {ECO:0000313|EMBL:EDI0959323.1}, CC907_14090
GN {ECO:0000313|EMBL:EDI0994720.1}, CC972_17870
GN {ECO:0000313|EMBL:EDI1140457.1}, D4Z37_19215
GN {ECO:0000313|EMBL:EBS6527912.1}, D6Q30_22060
GN {ECO:0000313|EMBL:EBS1100891.1}, DKA88_19515
GN {ECO:0000313|EMBL:EBW2554633.1}, DNM71_18470
GN {ECO:0000313|EMBL:EBV0722170.1}, DNV09_14725
GN {ECO:0000313|EMBL:EBV1033890.1}, DS261_19130
GN {ECO:0000313|EMBL:EBX7035499.1}, DUQ91_18395
GN {ECO:0000313|EMBL:EBS0138743.1}, DUV11_16940
GN {ECO:0000313|EMBL:EBS5365670.1}, DVG36_16265
GN {ECO:0000313|EMBL:EBY2835161.1}, EBC38_21945
GN {ECO:0000313|EMBL:EBZ4084402.1}, EID90_15010
GN {ECO:0000313|EMBL:EBZ9856157.1}, ELQ62_17900
GN {ECO:0000313|EMBL:ECA4925739.1}, EU445_18595
GN {ECO:0000313|EMBL:ECB1386454.1}, EVI00_17350
GN {ECO:0000313|EMBL:ECB2194436.1}, F9R11_19195
GN {ECO:0000313|EMBL:EDB3137602.1}, F9Y21_18980
GN {ECO:0000313|EMBL:EDB3628187.1}, FI137_15760
GN {ECO:0000313|EMBL:EBG5395265.1}, G2227_07875
GN {ECO:0000313|EMBL:HAE0480809.1}, G2244_19415
GN {ECO:0000313|EMBL:HAE0418665.1}, G3982_003016
GN {ECO:0000313|EMBL:HAE3629350.1}, G3V49_003890
GN {ECO:0000313|EMBL:HAE1998788.1}, G4I71_003256
GN {ECO:0000313|EMBL:HAE6055931.1}, G4L28_003023
GN {ECO:0000313|EMBL:HAE6908329.1}, G4P30_001392
GN {ECO:0000313|EMBL:HAE7598051.1}, G4Y41_001548
GN {ECO:0000313|EMBL:HAE9014944.1}, G4Y55_001797
GN {ECO:0000313|EMBL:HAE9579044.1}, G9264_002912
GN {ECO:0000313|EMBL:HAF7399398.1}, G9C68_001429
GN {ECO:0000313|EMBL:HAF0685917.1}, G9X37_000554
GN {ECO:0000313|EMBL:HAF7360072.1}, GDI29_17325
GN {ECO:0000313|EMBL:EDH3996755.1}, GND71_003725
GN {ECO:0000313|EMBL:HAE7811776.1}, K3U68_20805
GN {ECO:0000313|EMBL:QZA29226.1}, ZZ17_15960
GN {ECO:0000313|EMBL:ECV8217133.1};
OS Salmonella typhi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370 {ECO:0000313|EMBL:CAD09192.1, ECO:0000313|Proteomes:UP000000541};
RN [1] {ECO:0000313|EMBL:CAD09192.1, ECO:0000313|Proteomes:UP000000541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18 {ECO:0000313|EMBL:CAD09192.1,
RC ECO:0000313|Proteomes:UP000000541};
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.,
RA Rutherford K., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2] {ECO:0000313|EMBL:AAO71578.1, ECO:0000313|Proteomes:UP000002670}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2 {ECO:0000313|Proteomes:UP000002670}, and Ty2
RC {ECO:0000313|EMBL:AAO71578.1};
RX PubMed=12644504; DOI=10.1128/JB.185.7.2330-2337.2003;
RA Deng W., Liou S.R., Plunkett G.III., Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
RN [3] {ECO:0000313|EMBL:HAE0418665.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=09-1703 {ECO:0000313|EMBL:HAE3629350.1}, 09-1978
RC {ECO:0000313|EMBL:HAE6055931.1}, 09-1979
RC {ECO:0000313|EMBL:HAE7598051.1}, 10-1436
RC {ECO:0000313|EMBL:HAE1998788.1}, 11-2088
RC {ECO:0000313|EMBL:HAE6908329.1}, 12-0098
RC {ECO:0000313|EMBL:HAF7399398.1}, 12-0437
RC {ECO:0000313|EMBL:HAF7360072.1}, 12-2005
RC {ECO:0000313|EMBL:HAE9014944.1}, 13-0747
RC {ECO:0000313|EMBL:HAF0685917.1}, 13-7562
RC {ECO:0000313|EMBL:HAE9579044.1}, IP E.88.374
RC {ECO:0000313|EMBL:HAE7811776.1},
RC Sam_1c96eabc-5ba9-4785-8bb4-b62bc64a6574
RC {ECO:0000313|EMBL:HAE0418665.1}, and
RC Sam_2e1fd039-ec06-4964-b74e-443d7665d7a0
RC {ECO:0000313|EMBL:HAE0480809.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [4] {ECO:0000313|EMBL:HAE1998788.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=09-1703 {ECO:0000313|EMBL:HAE3629350.1}, 09-1978
RC {ECO:0000313|EMBL:HAE6055931.1}, 09-1979
RC {ECO:0000313|EMBL:HAE7598051.1}, 10-1436
RC {ECO:0000313|EMBL:HAE1998788.1}, 11-2088
RC {ECO:0000313|EMBL:HAE6908329.1}, 12-0098
RC {ECO:0000313|EMBL:HAF7399398.1}, 12-0437
RC {ECO:0000313|EMBL:HAF7360072.1}, 12-2005
RC {ECO:0000313|EMBL:HAE9014944.1}, 13-0747
RC {ECO:0000313|EMBL:HAF0685917.1}, 13-7562
RC {ECO:0000313|EMBL:HAE9579044.1}, IP E.88.374
RC {ECO:0000313|EMBL:HAE7811776.1},
RC Sam_1c96eabc-5ba9-4785-8bb4-b62bc64a6574
RC {ECO:0000313|EMBL:HAE0418665.1}, and
RC Sam_2e1fd039-ec06-4964-b74e-443d7665d7a0
RC {ECO:0000313|EMBL:HAE0480809.1};
RG NCBI Pathogen Detection Project;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:EBS0138743.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=116585 {ECO:0000313|EMBL:EDG8932456.1}, 132015
RC {ECO:0000313|EMBL:EDG8902423.1}, 14549
RC {ECO:0000313|EMBL:ECV8217133.1}, 186520
RC {ECO:0000313|EMBL:EDG8894195.1}, 189261
RC {ECO:0000313|EMBL:EDG8858206.1}, 257355
RC {ECO:0000313|EMBL:EBW2554633.1}, 338438
RC {ECO:0000313|EMBL:EDI1140457.1}, 339489
RC {ECO:0000313|EMBL:EDI0959323.1}, 348081
RC {ECO:0000313|EMBL:EDI0994720.1}, 365365
RC {ECO:0000313|EMBL:EDH5802516.1}, 524805
RC {ECO:0000313|EMBL:EBY2835161.1}, 531284
RC {ECO:0000313|EMBL:EBV1033890.1}, 539099
RC {ECO:0000313|EMBL:EBV0722170.1}, 550116
RC {ECO:0000313|EMBL:EBX7035499.1}, 550675
RC {ECO:0000313|EMBL:ECB1386454.1}, 550679
RC {ECO:0000313|EMBL:EBS5365670.1}, 568336
RC {ECO:0000313|EMBL:EBS0138743.1}, 588927
RC {ECO:0000313|EMBL:EBS6527912.1}, 606246
RC {ECO:0000313|EMBL:EBS1100891.1}, 619925
RC {ECO:0000313|EMBL:EBZ4084402.1}, 643219
RC {ECO:0000313|EMBL:EBZ9856157.1}, 656788
RC {ECO:0000313|EMBL:ECA4925739.1}, 673629
RC {ECO:0000313|EMBL:ECB2194436.1}, 731618
RC {ECO:0000313|EMBL:EBG5395265.1}, 814947
RC {ECO:0000313|EMBL:EDB3137602.1}, 815592
RC {ECO:0000313|EMBL:EDB3628187.1}, and 824494
RC {ECO:0000313|EMBL:EDH3996755.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:QZA29226.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ISP2825 {ECO:0000313|EMBL:QZA29226.1};
RA Lee G.Y., Song J.;
RT "Complete Genome Sequence of Salmonella enterica Serovar Typhi Strain
RT ISP2825.";
RL Submitted (AUG-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AE014613; AAO71578.1; -; Genomic_DNA.
DR EMBL; AL513382; CAD09192.1; -; Genomic_DNA.
DR EMBL; AAFJDY010000025; EBG5395265.1; -; Genomic_DNA.
DR EMBL; AAGUIA010000022; EBS0138743.1; -; Genomic_DNA.
DR EMBL; AAGULE010000063; EBS1100891.1; -; Genomic_DNA.
DR EMBL; AAGVVD010000020; EBS5365670.1; -; Genomic_DNA.
DR EMBL; AAGWES010000025; EBS6527912.1; -; Genomic_DNA.
DR EMBL; AAHEBT010000024; EBV0722170.1; -; Genomic_DNA.
DR EMBL; AAHEEH010000022; EBV1033890.1; -; Genomic_DNA.
DR EMBL; AAHHUX010000025; EBW2554633.1; -; Genomic_DNA.
DR EMBL; AAHLZU010000024; EBX7035499.1; -; Genomic_DNA.
DR EMBL; AAHNRO010000021; EBY2835161.1; -; Genomic_DNA.
DR EMBL; AAHRAJ010000040; EBZ4084402.1; -; Genomic_DNA.
DR EMBL; AAHSWZ010000020; EBZ9856157.1; -; Genomic_DNA.
DR EMBL; AAHUNO010000026; ECA4925739.1; -; Genomic_DNA.
DR EMBL; AAHWPO010000024; ECB1386454.1; -; Genomic_DNA.
DR EMBL; AAHWWI010000020; ECB2194436.1; -; Genomic_DNA.
DR EMBL; AAKUKE010000024; ECV8217133.1; -; Genomic_DNA.
DR EMBL; AALNBT010000023; EDB3137602.1; -; Genomic_DNA.
DR EMBL; AALNGB010000024; EDB3628187.1; -; Genomic_DNA.
DR EMBL; AAMFQS010000020; EDG8858206.1; -; Genomic_DNA.
DR EMBL; AAMFQZ010000024; EDG8894195.1; -; Genomic_DNA.
DR EMBL; AAMFRD010000022; EDG8902423.1; -; Genomic_DNA.
DR EMBL; AAMFRJ010000014; EDG8932456.1; -; Genomic_DNA.
DR EMBL; AAMHNJ010000020; EDH3996755.1; -; Genomic_DNA.
DR EMBL; AAMICL010000024; EDH5802516.1; -; Genomic_DNA.
DR EMBL; AAMJUX010000025; EDI0959323.1; -; Genomic_DNA.
DR EMBL; AAMJVG010000021; EDI0994720.1; -; Genomic_DNA.
DR EMBL; AAMJWL010000022; EDI1140457.1; -; Genomic_DNA.
DR EMBL; DAAQQG010000024; HAE0418665.1; -; Genomic_DNA.
DR EMBL; DAAQQU010000005; HAE0480809.1; -; Genomic_DNA.
DR EMBL; DAARDQ010000069; HAE1998788.1; -; Genomic_DNA.
DR EMBL; DAARRK010000031; HAE3629350.1; -; Genomic_DNA.
DR EMBL; DAASLV010000034; HAE6055931.1; -; Genomic_DNA.
DR EMBL; DAASSY010000031; HAE6908329.1; -; Genomic_DNA.
DR EMBL; DAASYX010000008; HAE7598051.1; -; Genomic_DNA.
DR EMBL; DAATAS010000024; HAE7811776.1; -; Genomic_DNA.
DR EMBL; DAATOU010000020; HAE9014944.1; -; Genomic_DNA.
DR EMBL; DAATPQ010000006; HAE9579044.1; -; Genomic_DNA.
DR EMBL; DAATYW010000005; HAF0685917.1; -; Genomic_DNA.
DR EMBL; DAAWCE010000009; HAF7360072.1; -; Genomic_DNA.
DR EMBL; DAAWDS010000031; HAF7399398.1; -; Genomic_DNA.
DR EMBL; CP080960; QZA29226.1; -; Genomic_DNA.
DR RefSeq; NP_458506.1; NC_003198.1.
DR RefSeq; WP_000226433.1; NZ_WSUR01000027.1.
DR AlphaFoldDB; Q8Z1V7; -.
DR STRING; 220341.gene:17588236; -.
DR KEGG; stt:t4114; -.
DR KEGG; sty:STY4404; -.
DR PATRIC; fig|220341.7.peg.4502; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_7_1_6; -.
DR OMA; EPDRLHR; -.
DR OrthoDB; 9807558at2; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF22; TRANSCRIPTIONAL REPRESSOR ICLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..86
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 87..272
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 29660 MW; 0A9E6F6107C95C92 CRC64;
MVAPVPAKRG RKPAATTAPV TGQVQSLTRG LKLLEWIAES NGSVALTELA QQAGLPNSTT
HRLLTTMQQQ GFVRQVGELG HWAVGAHAFI VGSSFLQSRN LLAIVHPILR KLMEDSGETV
NLAVLDQSDH QAIIIDQVQC TQLMRMSAPI GGKLPMHASG AGKAFLSQLS EEQVTSLLHR
KGLHAYTHAT LVSPLHLKDD LAQTRKRGYS FDDEEHALGL RCVASCIYDE HREPFAALSI
SGPCSRITDD RVTELGAMVI KAAKEVTLAY GGFR
//
