ID Q97CU7_THEVO Unreviewed; 244 AA.
AC Q97CU7;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Cytochrome-c3 hydrogenase [sulfhydrogenase] gamma subunit {ECO:0000313|EMBL:BAB59146.1};
GN ORFNames=TVG0005131 {ECO:0000313|EMBL:BAB59146.1};
OS Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS 15438 / GSS1).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC Thermoplasmataceae; Thermoplasma.
OX NCBI_TaxID=273116 {ECO:0000313|EMBL:BAB59146.1, ECO:0000313|Proteomes:UP000001017};
RN [1] {ECO:0000313|EMBL:BAB59146.1, ECO:0000313|Proteomes:UP000001017}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
RC {ECO:0000313|Proteomes:UP000001017};
RX PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT Thermoplasma volcanium.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|PIRSR:PIRSR006816-2};
CC Note=Binds 1 [2Fe-2S] cluster per subunit.
CC {ECO:0000256|PIRSR:PIRSR006816-2};
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DR EMBL; BA000011; BAB59146.1; -; Genomic_DNA.
DR RefSeq; WP_010916261.1; NC_002689.2.
DR AlphaFoldDB; Q97CU7; -.
DR STRING; 273116.gene:9380769; -.
DR PaxDb; 273116-14324218; -.
DR DNASU; 1441489; -.
DR GeneID; 1441489; -.
DR KEGG; tvo:TVG0005131; -.
DR eggNOG; arCOG02199; Archaea.
DR HOGENOM; CLU_003827_1_1_2; -.
DR OrthoDB; 35401at2157; -.
DR PhylomeDB; Q97CU7; -.
DR Proteomes; UP000001017; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd06221; sulfite_reductase_like; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR012165; Cyt_c3_hydrogenase_gsu.
DR InterPro; IPR019480; Dihydroorotate_DH_Fe-S-bd.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR43513:SF1; ANAEROBIC SULFITE REDUCTASE SUBUNIT B; 1.
DR PANTHER; PTHR43513; DIHYDROOROTATE DEHYDROGENASE B (NAD(+)), ELECTRON TRANSFER SUBUNIT; 1.
DR Pfam; PF10418; DHODB_Fe-S_bind; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR PIRSF; PIRSF006816; Cyc3_hyd_g; 1.
DR PRINTS; PR00371; FPNCR.
DR PRINTS; PR00410; PHEHYDRXLASE.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714, ECO:0000256|PIRSR:PIRSR006816-2};
KW Iron {ECO:0000256|PIRSR:PIRSR006816-2};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PIRSR:PIRSR006816-
KW 2}; Metal-binding {ECO:0000256|PIRSR:PIRSR006816-2}.
FT DOMAIN 88..185
FT /note="Oxidoreductase FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF00175"
FT DOMAIN 204..235
FT /note="Dihydroorotate dehydrogenase electron transfer
FT subunit iron-sulphur cluster binding"
FT /evidence="ECO:0000259|Pfam:PF10418"
FT BINDING 209
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000256|PIRSR:PIRSR006816-2"
FT BINDING 214
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000256|PIRSR:PIRSR006816-2"
FT BINDING 217
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000256|PIRSR:PIRSR006816-2"
FT BINDING 225
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000256|PIRSR:PIRSR006816-2"
SQ SEQUENCE 244 AA; 26996 MW; BF613C206C94838D CRC64;
METADTYTIV LTERNMGYAG QFYMVSKEGI GEAPISVGSG YGNPLMFSIK AVGSVTKGIM
NDPYGEIGIR GPYGNVWPWK SYEHVVAIAG GIGIPPIKAL IEDMQGHTSL DKLTVLYGAR
SPSDIVYRSE IETWKEEMDF RITVDKGDEN WRGHVGVVTT LVPEIKEYNH GAAFVIGPPV
MMKFSVKSLL DAGFAEDNIY LSLERRMECG IGVCGHCNIG RWYACEDGPI FKYSDTKEEP
ELFL
//
