ID Q97D10_CLOAB Unreviewed; 385 AA.
AC Q97D10;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=XylR transcriptional regulator {ECO:0000313|EMBL:AAK81594.1};
GN Name=xylR {ECO:0000313|EMBL:AAK81594.1};
GN OrderedLocusNames=CA_C3673 {ECO:0000313|EMBL:AAK81594.1};
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK81594.1, ECO:0000313|Proteomes:UP000000814};
RN [1] {ECO:0000313|EMBL:AAK81594.1, ECO:0000313|Proteomes:UP000000814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC {ECO:0000313|Proteomes:UP000000814};
RX PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; AE001437; AAK81594.1; -; Genomic_DNA.
DR PIR; G97350; G97350.
DR RefSeq; NP_350254.1; NC_003030.1.
DR RefSeq; WP_010966934.1; NC_003030.1.
DR AlphaFoldDB; Q97D10; -.
DR STRING; 272562.CA_C3673; -.
DR GeneID; 45000171; -.
DR KEGG; cac:CA_C3673; -.
DR PATRIC; fig|272562.8.peg.3862; -.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_1_9; -.
DR OrthoDB; 9796533at2; -.
DR Proteomes; UP000000814; Chromosome.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000814}.
SQ SEQUENCE 385 AA; 43440 MW; EC37EA6E4E495879 CRC64;
MFDIDQNSNK GKILNLLYRK RELTKLDISN EIGVSVPTVI SNVNELIREG FVEESGVASS
TGGRKPIIVS FIPNSRYAFG VDINPYMARV VLTNLDLEIK YDVEFLIEEL KDIKSIMKRI
SLIVKEALEF TKIDEKKVLG IGFSLQGTVD EENLVLKRAI NIGVKDWDFK LFENLFQFPL
FIENEANAAA LAELKIGIAK EERNLVYISV SSGLGTGIVI EGQLYKGKNK RAGEMGHMTL
VPHGKLCRCG RKGCWEMYAS QKALLDEFNE LSDVKVTKLE QFFNLIMIKN KVAEKCLNNY
LNNLASGIQN IVLIFDPHYI VLGGEISGYS DVYLDSLKDK IFDENEFYNR GDFKLFPSRL
KRNSSILGAA LLPIQKAFLI EQDVI
//
