ID   Q97LT2_CLOAB            Unreviewed;       551 AA.
AC   Q97LT2;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 128.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000256|ARBA:ARBA00014415};
DE   AltName: Full=Chaperone protein dnaK {ECO:0000256|ARBA:ARBA00017249};
DE   AltName: Full=HSP70 {ECO:0000256|ARBA:ARBA00033103};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000256|ARBA:ARBA00030945};
DE   AltName: Full=Heat shock protein 70 {ECO:0000256|ARBA:ARBA00030019};
GN   Name=dnaK {ECO:0000313|EMBL:AAK78452.1};
GN   OrderedLocusNames=CA_C0472 {ECO:0000313|EMBL:AAK78452.1};
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK78452.1, ECO:0000313|Proteomes:UP000000814};
RN   [1] {ECO:0000313|EMBL:AAK78452.1, ECO:0000313|Proteomes:UP000000814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC   {ECO:0000313|Proteomes:UP000000814};
RX   PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA   Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000256|ARBA:ARBA00002290}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR   EMBL; AE001437; AAK78452.1; -; Genomic_DNA.
DR   PIR; A96958; A96958.
DR   RefSeq; NP_347112.1; NC_003030.1.
DR   RefSeq; WP_010963794.1; NC_003030.1.
DR   AlphaFoldDB; Q97LT2; -.
DR   STRING; 272562.CA_C0472; -.
DR   GeneID; 44996981; -.
DR   KEGG; cac:CA_C0472; -.
DR   PATRIC; fig|272562.8.peg.671; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_0_0_9; -.
DR   OrthoDB; 9766019at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10170; HSP70_NBD; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR   Pfam; PF00012; HSP70; 3.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
SQ   SEQUENCE   551 AA;  61692 MW;  D5E7D47A318E8D0C CRC64;
     MNEIFGIDLG TTYSCISYVD EYGRPVVVPN AENERITPSV VFFDGDNVIV GDVAKENSKM
     YPEDVVSFVK RSMGDENFYF EHGGKNYHAE EISSFILRKL ISDAENNLGQ KINDVVITCP
     AYFGINEREA TKLAGEIAGL NVKAIINEPT AAAVAYGVDY DKDKVVLVYD LGGGTFDVTM
     IDVKKDSIKV ICTGGDHNLG GKDWDDALIA YMAEQYKEIT GNDKDILEDP ETCQELQLLA
     ERVKKTLSQR EKAPISINYE GERAKIEITR QKFNELTYDL LQRTVNLMDD MLKEAAKKNY
     TSFDEILLVG GSSRMPQVEE IIKNKYNIEP KVFDPDEAVS KGAALYGWKL SVNDELVRRI
     SEETGKDIED IKKSIDEKSI DENVVEAAAK RVADDTGYTL SAVKASNVKV VNVVSKSFGV
     VTYNNEEKEV VYNLIIKNSE VPYEFTERFG TREENQENVM IKIVEDELSD KIVDIAYGNE
     IGEAELVLPE NLPKNSPVDI TFKLNEEGRL EIKAIEAVEK REISTSIETS SVIKGKDLEE
     AKERNKNIEV S
//