ID Q97M07_CLOAB Unreviewed; 344 AA.
AC Q97M07;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=KDG operon repressor (Gene kdgR), LacI family {ECO:0000313|EMBL:AAK78373.1};
GN Name=kdgR {ECO:0000313|EMBL:AAK78373.1};
GN OrderedLocusNames=CA_C0393 {ECO:0000313|EMBL:AAK78373.1};
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK78373.1, ECO:0000313|Proteomes:UP000000814};
RN [1] {ECO:0000313|EMBL:AAK78373.1, ECO:0000313|Proteomes:UP000000814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC {ECO:0000313|Proteomes:UP000000814};
RX PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
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DR EMBL; AE001437; AAK78373.1; -; Genomic_DNA.
DR PIR; B96948; B96948.
DR RefSeq; NP_347033.1; NC_003030.1.
DR RefSeq; WP_010963715.1; NC_003030.1.
DR AlphaFoldDB; Q97M07; -.
DR STRING; 272562.CA_C0393; -.
DR DNASU; 1116576; -.
DR GeneID; 44996903; -.
DR KEGG; cac:CA_C0393; -.
DR PATRIC; fig|272562.8.peg.588; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_9; -.
DR OrthoDB; 369222at2; -.
DR Proteomes; UP000000814; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06283; PBP1_RegR_EndR_KdgR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF138; HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 7..62
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 11..30
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 344 AA; 38394 MW; 89833D97F232E3F1 CRC64;
MDNNKKVVID DVAKLAGVSK ATISRYLNGK FEYMSEKTKD RIKESIEELN YRPNNIARSL
KSNKSKLIGV VIADLTNPFS SIIIKGIGDE CKARGYNMVI ANSDNDVKQE EEYIKSLLDQ
RVEGIIVNST GYNEEFLLSI KERGIPVSMV DRTFCEDKVD SVKSNNYDIT VETINYLIDA
GFNSLCFFTE RLDNIKPRIE RERAFIDVCS KRLKKENYNI SVVDYSKAGN LEVNIYKFLN
NYSGKKAIFA VNGVVLLHTL SAINKLNINV PKDLGICGYD NWGWAALIPP GITTISQPSY
EMGSEAAKLV LDRIEGKASL GAVCKTLSAK LEIRGSTIPL NMPT
//
