ID Q98KX1_RHILO Unreviewed; 817 AA.
AC Q98KX1;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Dimethylglycine dehydrogenase {ECO:0000313|EMBL:BAB48692.1};
GN OrderedLocusNames=mlr1280 {ECO:0000313|EMBL:BAB48692.1};
OS Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
OS (Mesorhizobium loti (strain MAFF 303099)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=266835 {ECO:0000313|EMBL:BAB48692.1, ECO:0000313|Proteomes:UP000000552};
RN [1] {ECO:0000313|EMBL:BAB48692.1, ECO:0000313|Proteomes:UP000000552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 29417 / CECT 9101 / MAFF 303099
RC {ECO:0000313|Proteomes:UP000000552};
RX PubMed=11214968; DOI=10.1093/dnares/7.6.331;
RA Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S.,
RA Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y.,
RA Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y.,
RA Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M.,
RA Tabata S.;
RT "Complete genome structure of the nitrogen-fixing symbiotic bacterium
RT Mesorhizobium loti.";
RL DNA Res. 7:331-338(2000).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; BA000012; BAB48692.1; -; Genomic_DNA.
DR RefSeq; WP_010910046.1; NC_002678.2.
DR AlphaFoldDB; Q98KX1; -.
DR KEGG; mlo:mlr1280; -.
DR PATRIC; fig|266835.9.peg.1037; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_0_5; -.
DR Proteomes; UP000000552; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 9..373
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 377..431
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 434..703
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 728..806
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 817 AA; 91260 MW; D6CEE09964D162EF CRC64;
MAGLPSTARV VIIGGGVVGT SSLYHLAKAG WTDCVLLEKN ELTSGSTWHA AGNVPTFSSS
WSLMNMQRYS TELYRGLADA VDYPMNYHVT GSLRLAHTKE RMQEFQRAKG MGRYQGMDID
VVGVDEIKRR YPFIETHDLK GALYDPSDGD IDPAQLTQAL AKGARDLGAK IIRFCPVTGV
RREKDEWVVT TPQGEIRCEI VVNAAGYRAA EVGRMFGREV PMMVMSHQYI LFEEIPELAA
WSKEQGKKLP LLRDVDTSYY LRQEKAGMNL GPYERNCRAH WATPGDPMPE DFSFQLFPDD
LDRLEHYLAD AVARVPILGT AGLSKVINGP IPYAPDGNPL IGPMPGVPNA FEACVFTFGI
AQGGGAGKVL AEWVTQGQTE WDMWSCDPRR FTSFASAPDY CVAKGMEIYG NEYAIQFPRH
AWPEGRDRKL SPIHDRTKAL GGRFDAYNGW ERATWYAKDG DDISEEATLT FRRDGPWQHR
VREECLAVRD AAGILDLPGF SRFRLQGPGA RDWLATMITG LVPKPGRIGL GYFSDDKGRI
VTEMSIMALA EDLFFLITAS VAEQHDFEWL QYHLPQPNEL TLQNLTEAFS CQILSGPKSR
DILSELTAAD LSLPWLSHQS VQISGHWCQL VRVSFVGELG WEIHTKVDDT AAVFDAVWAA
GQKHGLKPFG MYALDSLRLE KGYRTWKGDL STDYSILQGG LERFVKWEKP DFRGKAALQN
EKQQGVKKRF VTLVVENPGD CDAPYMSTLW HGGQIVGETT SGGWGHRIDK SIALGMLRVD
LTEPGTSVEV EIFGDRFQAV VQKDEPLWDP RNERLRA
//
