ID   Q9ACN0_STRPY            Unreviewed;       427 AA.
AC   Q9ACN0;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=SclB protein {ECO:0000313|EMBL:CAC33780.1};
GN   Name=sclB {ECO:0000313|EMBL:CAC33780.1};
OS   Streptococcus pyogenes.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314 {ECO:0000313|EMBL:CAC33780.1};
RN   [1] {ECO:0000313|EMBL:CAC33780.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=733 {ECO:0000313|EMBL:CAC33780.1};
RX   PubMed=11158359;
RA   Whatmore A.M.;
RT   "Streptococcus pyogenes sclB encodes a putative hypervariable surface
RT   protein with a collagen-like repetitive structure.";
RL   Microbiology 147:419-429(2001).
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DR   EMBL; AJ301813; CAC33780.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9ACN0; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR019950; M_anchor.
DR   NCBIfam; NF038329; gly_rich_SclB; 1.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24023:SF1082; COLLAGEN ALPHA-1(X) CHAIN; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   PRINTS; PR00015; GPOSANCHOR.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           41..427
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039440951"
FT   TRANSMEM        403..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          393..427
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          108..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..178
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..315
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..345
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   427 AA;  43495 MW;  D0ED98EE44464EDC CRC64;
     MNKTKQNKTK QNKTKQNSLL CRYGLTSAAA LLLTFGGASA VKADAASIKE VQAKLQSYRQ
     ALPRFKNYNT NTPNSGVEDT PTYKYLTEME DKLNRYLETL DEGLDQLQGA KGEAGPAGPK
     GPAGEKGERG ERGETGPAGP AGKDGDAGAQ GPMGPAGPQG PRGDKGETGD KGDQGPAGKD
     GERGPVGPAG KDGQDGLPGK DGKDGQDGQD GLPGKDGKDG QNGKDGLPGK DGKDGQNGKD
     GLPGKDGKDG QDGQDGLPGK DGKDGQNGKD GLPGKDGKDG QNGKDGLPGK DGKDGQNGKD
     GLPGKDGKDG QNGRDGLPGK DGQPGKPAPK TPEVPQKPDT APHTPKTPQI PGQSKDVTPA
     PQNPSNRGLN KPQTQGGNQL AKTPAAHDTH RQLPATGETT NPFFTAAAVA IMTTAGVVAV
     AKRQENN
//