ID Q9C8X4_ARATH Unreviewed; 279 AA.
AC Q9C8X4;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 24-JAN-2024, entry version 172.
DE RecName: Full=GrpE protein homolog {ECO:0000256|RuleBase:RU000640};
GN Name=CGE2 {ECO:0000313|TAIR:AT1G36390};
GN OrderedLocusNames=At1g36390 {ECO:0000313|Araport:AT1G36390,
GN ECO:0000313|EMBL:AEE31864.1};
GN ORFNames=F7F23.11 {ECO:0000313|EMBL:AAG52200.1}, F7F23_11
GN {ECO:0000313|EMBL:AEE31864.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAG52200.1};
RN [1] {ECO:0000313|EMBL:AEE31864.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|EMBL:AAG52200.1}
RP NUCLEOTIDE SEQUENCE.
RA Lin X., Kaul S., Town C.D., Benito M., Creasy T.H., Haas B.J., Wu D.,
RA Maiti R., Ronning C.M., Koo H., Fujii C.Y., Utterback T.R., Barnstead M.E.,
RA Bowman C.L., White O., Nierman W.C., Fraser C.M.;
RT "Arabidopsis thaliana chromosome 1 BAC F7F23 genomic sequence.";
RL Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAG52200.1}
RP NUCLEOTIDE SEQUENCE.
RA Town C.D., Kaul S.;
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAL38838.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Liu S.X., Sakano H., Pham P.K., Banh J., Chung M.K.,
RA Goldsmith A.D., Lee J.M., Quach H.L., Toriumi M., Yu G., Bowser L.,
RA Carninci P., Chen H., Cheuk R., Hayashizaki Y., Ishida J., Jones T.,
RA Kamiya A., Karlin-Neumann G., Kawai J., Kim C., Lam B., Lin J., Miranda M.,
RA Narusaka M., Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Full Length cDNA Clones.";
RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AAM51251.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Banh J., Chan M.M., Chang C.H., Chang E., Dale J.M., Deng J.M.,
RA Goldsmith A.D., Lee J.M., Onodera C.S., Quach H.L., Tang C., Toriumi M.,
RA Wu H.C., Yamamura Y., Yu G., Bowser L., Carninci P., Chen H., Cheuk R.,
RA Hayashizaki Y., Ishida J., Jones T., Kamiya A., Karlin-Neumann G.,
RA Kawai J., Kim C., Lam B., Lin J., Miranda M., Narusaka M., Nguyen M.,
RA Palm C.J., Sakurai T., Satou M., Seki M., Shinn P., Southwick A.,
RA Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Open Reading Frame (ORF) Clones.";
RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AEE31864.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:AEE31864.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Essential component of the PAM complex, a complex required
CC for the translocation of transit peptide-containing proteins from the
CC inner membrane into the mitochondrial matrix in an ATP-dependent
CC manner. {ECO:0000256|RuleBase:RU000640}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|RuleBase:RU000640}.
CC -!- SIMILARITY: Belongs to the GrpE family. {ECO:0000256|ARBA:ARBA00009054,
CC ECO:0000256|RuleBase:RU004478}.
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DR EMBL; AC021199; AAG52200.1; -; Genomic_DNA.
DR EMBL; AY065397; AAL38838.1; -; mRNA.
DR EMBL; AY117176; AAM51251.1; -; mRNA.
DR EMBL; CP002684; AEE31864.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31865.1; -; Genomic_DNA.
DR PIR; H86484; H86484.
DR RefSeq; NP_564475.1; NM_103325.4.
DR RefSeq; NP_849751.1; NM_179420.2.
DR AlphaFoldDB; Q9C8X4; -.
DR SMR; Q9C8X4; -.
DR STRING; 3702.Q9C8X4; -.
DR PaxDb; 3702-AT1G36390-2; -.
DR ProteomicsDB; 178846; -.
DR EnsemblPlants; AT1G36390.1; AT1G36390.1; AT1G36390.
DR EnsemblPlants; AT1G36390.2; AT1G36390.2; AT1G36390.
DR GeneID; 840545; -.
DR Gramene; AT1G36390.1; AT1G36390.1; AT1G36390.
DR Gramene; AT1G36390.2; AT1G36390.2; AT1G36390.
DR KEGG; ath:AT1G36390; -.
DR Araport; AT1G36390; -.
DR TAIR; AT1G36390; CGE2.
DR eggNOG; KOG3003; Eukaryota.
DR HOGENOM; CLU_057217_5_1_1; -.
DR OMA; VSYQGIY; -.
DR OrthoDB; 36313at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8X4; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; IDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; IDA:TAIR.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0005507; F:copper ion binding; HDA:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IPI:TAIR.
DR GO; GO:0042803; F:protein homodimerization activity; IPI:TAIR.
DR GO; GO:0043621; F:protein self-association; IPI:TAIR.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0009408; P:response to heat; IEP:TAIR.
DR CDD; cd00446; GrpE; 1.
DR Gene3D; 3.90.20.20; -; 1.
DR Gene3D; 2.30.22.10; Head domain of nucleotide exchange factor GrpE; 1.
DR HAMAP; MF_01151; GrpE; 1.
DR InterPro; IPR000740; GrpE.
DR InterPro; IPR013805; GrpE_coiled_coil.
DR InterPro; IPR009012; GrpE_head.
DR PANTHER; PTHR21237:SF40; CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2; 1.
DR PANTHER; PTHR21237; GRPE PROTEIN; 1.
DR Pfam; PF01025; GrpE; 1.
DR PRINTS; PR00773; GRPEPROTEIN.
DR SUPFAM; SSF58014; Coiled-coil domain of nucleotide exchange factor GrpE; 1.
DR SUPFAM; SSF51064; Head domain of nucleotide exchange factor GrpE; 1.
DR PROSITE; PS01071; GRPE; 1.
PE 1: Evidence at protein level;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU000640};
KW Mitochondrion {ECO:0000256|RuleBase:RU000640};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q9C8X4,
KW ECO:0007829|ProteomicsDB:Q9C8X4};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Stress response {ECO:0000313|EMBL:AAG52200.1}.
SQ SEQUENCE 279 AA; 31223 MW; 2E55690633116141 CRC64;
MAISFAIDPS ISPCFSFSSP SSSSKTLPLR NNLHFHGRPS PISPLISKPS RKFPIFSAHQ
TNNSEEANSK QQADVKTLIR SYKQALLNGD ETSVTEIETM FCKIEKEKNK MDQKVLSLSM
KIASEKEMKI RLQADFDNTR KKLDKDRLST ESNAKVQILK SLLPIIDSFE KAKLQVRVDT
DKEKKIDTSY QGIYRQFVEV LRYLRVSVIA TVGKPFDPLL HEAISREESE AVKAGIITEE
LNKGFVLGDR VLRPAKVKVS LGPVNKKTPS AAEEITPSA
//
