ID Q9CBQ8_MYCLE Unreviewed; 252 AA.
AC Q9CBQ8;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Enoyl-CoA hydratase/isomerase {ECO:0000313|EMBL:CAC30677.1};
GN OrderedLocusNames=ML1724 {ECO:0000313|EMBL:CAC30677.1};
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631 {ECO:0000313|EMBL:CAC30677.1, ECO:0000313|Proteomes:UP000000806};
RN [1] {ECO:0000313|EMBL:CAC30677.1, ECO:0000313|Proteomes:UP000000806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN {ECO:0000313|EMBL:CAC30677.1,
RC ECO:0000313|Proteomes:UP000000806};
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; AL583923; CAC30677.1; -; Genomic_DNA.
DR PIR; F87124; F87124.
DR RefSeq; NP_302187.1; NC_002677.1.
DR RefSeq; WP_010908508.1; NC_002677.1.
DR AlphaFoldDB; Q9CBQ8; -.
DR SMR; Q9CBQ8; -.
DR STRING; 272631.gene:17575569; -.
DR KEGG; mle:ML1724; -.
DR PATRIC; fig|272631.5.peg.3247; -.
DR Leproma; ML1724; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_6_11; -.
DR OrthoDB; 8452484at2; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR11941:SF54; ENOYL-COA HYDRATASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11941; ENOYL-COA HYDRATASE-RELATED; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000806}.
SQ SEQUENCE 252 AA; 26586 MW; 82210AEE4983A89F CRC64;
MSEFVNIVVS DGSQDAGLAI LLLSRPPTNA MTRQFYREIA MAADELGRRD DVAAVILFGG
HDIFSAGDDM QELRTLTAVE AGVAAEVRRQ AVDAVATIPK PTVAAITGYA LGAGLTLALA
ADWRVSGDNV KFGATEILAD LVPDGDGLAR LTRVAGVSRA KDLVFSGRFF DAAEALALGL
IDDMVAPDDV YDIAAAWARR FLDGLPHALA AAKAGINEVF DLEPAERIAA ERRRYVEVFA
AAQPSLLLGG CD
//
