ID Q9EWD7_STRCO Unreviewed; 483 AA.
AC Q9EWD7;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Monooxygenase {ECO:0000313|EMBL:CAC17658.1};
GN OrderedLocusNames=SCO4870 {ECO:0000313|EMBL:CAC17658.1};
GN ORFNames=SCK20.11c {ECO:0000313|EMBL:CAC17658.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC17658.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAC17658.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; AL939121; CAC17658.1; -; Genomic_DNA.
DR RefSeq; NP_629024.1; NC_003888.3.
DR RefSeq; WP_011029917.1; NZ_VNID01000016.1.
DR AlphaFoldDB; Q9EWD7; -.
DR STRING; 100226.gene:17762519; -.
DR PaxDb; 100226-SCO4870; -.
DR PATRIC; fig|100226.15.peg.4949; -.
DR eggNOG; COG0654; Bacteria.
DR HOGENOM; CLU_009665_20_3_11; -.
DR InParanoid; Q9EWD7; -.
DR OrthoDB; 8670884at2; -.
DR PhylomeDB; Q9EWD7; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR Gene3D; 3.30.70.2450; -; 1.
DR Gene3D; 3.40.30.120; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF21274; Rng_hyd_C; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Monooxygenase {ECO:0000313|EMBL:CAC17658.1};
KW Oxidoreductase {ECO:0000313|EMBL:CAC17658.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 15..355
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 483 AA; 50754 MW; C93F00B2BDE97CFB CRC64;
MNVTDTHVAG TDVPDTDVLI VGAGPTGLTL GVELARRGVH ALVLEGAGEL FPGSRGKGFQ
PRTMEVFDDL GVVDALHAVG GPYPIGMIWR NGERVGEHHM FDPAEPSEDS PYNRAWMVPQ
WRTQEILAAR LAELGGRVAF RHEVVGVAQD AEGVTAHLSS GGTVRARYLV AADGGRSAAR
RALGIGMTGE TVDPSPTLVA DVRISGLDRD NWHVFPPGDG VDLLAVCPLA GTEDFQVMAR
FPEGADLDTS ADGVRKVVAE RSHIAAEDVT EVRWVSDFRP RAALADRFRD GRVFLAGDAA
HVHSPAGGQG LNTSVQDAYN LGWKLGAVLK GDAPAALLDS YEEERRPIAA QMLDLSTAVH
RGEVRRGGAT RQLGIGYRDS SLTVETRGAV GEEAVRAGDR APDGRVDGVR LFDAFRGPHW
TLLALGVDAP GGGVGAAVPV VRGGAHGAYG AGLFLVRPDG YVGWAGDTPD GLGAYLGRFG
LGA
//
