ID Q9FAM9_PSECI Unreviewed; 296 AA.
AC Q9FAM9;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:BAB17404.1};
OS Pseudomonas cichorii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=36746 {ECO:0000313|EMBL:BAB17404.1};
RN [1] {ECO:0000313|EMBL:BAB17404.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCPPB 943 {ECO:0000313|EMBL:BAB17404.1};
RA Yamamoto S., Kasai H., Arnold D.L., Jackson R.W., Vivian A., Harayama S.;
RT "Phylogeny of the genus Pseudomonas: intrageneric structure reconstructed
RT from the nucleotide sequences of gyrB and rpoD genes.";
RL Microbiology (Mosc.) 146:2385-2394(2000).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB039434; BAB17404.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9FAM9; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:BAB17404.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 108..277
FT /note="DNA topoisomerase type IIA subunit B"
FT /evidence="ECO:0000259|Pfam:PF00204"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAB17404.1"
FT NON_TER 296
FT /evidence="ECO:0000313|EMBL:BAB17404.1"
SQ SEQUENCE 296 AA; 32794 MW; 69668BA9CEBB92A9 CRC64;
GGLHGVGVSV VNALSEVLQL TVRRSGKIWE QTYVHGVPQE PMKIVGESDS TGTQIHFKPS
ADTFKNIHFS WDILAKRIRE LSFLNSGVGI FLKDERSGKE ELFKYEGGLR AFVEYLNTNK
TAVNQVFHFN VQRDDGVGVE IALQWNDSFN ENLLCFTNNI PQRDGGTHLV GFRSALTRNL
NNYIEQEGLA KKHKVATTGD DAREGLTAII SVKVPDPKFS SQTKDKLVSS EVKTAVEQEM
GKYFSDFLLE NPNEAKAVVG KMLDAARARE AARKAREMTR RKGALDIAGL PGKLAD
//
