ID Q9GP88_CIOIN Unreviewed; 207 AA.
AC Q9GP88; A0A1W2VN79;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 24-JAN-2024, entry version 127.
DE SubName: Full=Distal-less {ECO:0000313|EMBL:CAC08210.1};
GN Name=Dll-B {ECO:0000313|EMBL:CAC08210.1};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|EMBL:CAC08210.1};
RN [1] {ECO:0000313|EMBL:CAC08210.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11091088; DOI=10.1016/S0925-4773(00)00474-3;
RA Caracciolo A., Di Gregorio A., Aniello F., Di Lauro R., Branno M.;
RT "Identification and developmental expression of three Distal-less homeobox
RT containing genes in the ascidian Ciona intestinalis.";
RL Mech. Dev. 99:173-176(2000).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the distal-less homeobox family.
CC {ECO:0000256|ARBA:ARBA00007916}.
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DR EMBL; AJ278697; CAC08210.1; -; mRNA.
DR RefSeq; NP_001027672.1; NM_001032500.1.
DR AlphaFoldDB; Q9GP88; -.
DR GeneID; 445682; -.
DR KEGG; cin:445682; -.
DR CTD; 445682; -.
DR OrthoDB; 2969529at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24327; HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR24327:SF81; HOMEOTIC PROTEIN DISTAL-LESS-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 19..79
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 21..80
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 23693 MW; 5EC8B9CC8DCA05A3 CRC64;
MGTSTTEQPN TSVNTSKSKK KRNPRTVYSN YQLQELHMYF KKVQYLALPE RARLAAALGL
TQTQVKVWFQ NRRSKIKKLL KSGVVQDLDE IGIQSVIDNQ APDFDGEPPA ESVKRARSYD
DHVDAESLQW NAPKQHCPSN EGPDIHGRTR NCTLSIITNE PSRKRNPTFS PRSHQPNDEL
PTLPAVQLFP RNEQQPSFWS QLRSERI
//
