ID Q9HT97_PSEAE Unreviewed; 582 AA.
AC Q9HT97;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE RecName: Full=PhoU domain-containing protein {ECO:0000259|Pfam:PF01895};
GN OrderedLocusNames=PA5473 {ECO:0000313|EMBL:AAG08858.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG08858.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG08858.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE004091; AAG08858.1; -; Genomic_DNA.
DR PIR; C82961; C82961.
DR RefSeq; NP_254160.1; NC_002516.2.
DR RefSeq; WP_003096931.1; NZ_QZGE01000012.1.
DR AlphaFoldDB; Q9HT97; -.
DR SMR; Q9HT97; -.
DR STRING; 208964.PA5473; -.
DR PaxDb; 208964-PA5473; -.
DR GeneID; 880370; -.
DR KEGG; pae:PA5473; -.
DR PATRIC; fig|208964.12.peg.5737; -.
DR PseudoCAP; PA5473; -.
DR HOGENOM; CLU_025623_2_1_6; -.
DR InParanoid; Q9HT97; -.
DR OrthoDB; 5778511at2; -.
DR PhylomeDB; Q9HT97; -.
DR BioCyc; PAER208964:G1FZ6-5601-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; TIGR01013; 2a58; 1.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR PANTHER; PTHR10010:SF39; PHOU DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 1.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 340..423
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT REGION 536..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 63262 MW; E45F740F4EC7C063 CRC64;
MLKLLDLLSA VALLVWGTHI VRTGILRVYG ADLRRILSRS VEKRPLAFAA GIGVTALVQS
SNATALLATS FVAQGLMALA PALAIMLGAD VGTALMARVL TLDLSWLSPL LIFFGVIFFL
SRKQTRLGQL GRVFIGLGLI ILALQLIVAA AEPMTQAKGV KVLFSSLTGD IMLDALTGAL
FAMISYSSLA AVLLTATLAA SKVISLKVAL CLVVGANLGS GILAMLSATA QNAAGRRVAL
GSLLFKVAGC LLVLPLVGPL ADWMDHWQFS TAELVIAFHV LYNAARCLAC LPLTNAMASF
CTRVMPDRAL PDDVARPRHL DPAALDTPSL ALANAVRETL RMGDTVEQML NNLMQIIRGG
DPLLGKDIRK LDDDVDALYT AIKLYLARMP REDLSERDSR RWAEIIELAI NLEQAGDIIE
HMLAAVQDKK TSRSRSFSDT GLEEIGTLYQ QLVSNLRLGL SVFLNGDLDS AKRLRRAKQR
FRLQERRYAH AHVDRLHQQV VQSIETSSLH LDLISDMKRL NSLFCAIAYA VLDNPDAPSS
AADEGTRRDE DDWADEVDDM TSAPLAEPAL AEERAETRRS RH
//
