ID Q9HUN5_PSEAE Unreviewed; 680 AA.
AC Q9HUN5;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=GGDEF domain-containing protein {ECO:0000259|PROSITE:PS50887};
GN OrderedLocusNames=PA4929 {ECO:0000313|EMBL:AAG08314.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG08314.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG08314.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE004091; AAG08314.1; -; Genomic_DNA.
DR PIR; C83029; C83029.
DR RefSeq; NP_253616.1; NC_002516.2.
DR RefSeq; WP_010895689.1; NC_002516.2.
DR AlphaFoldDB; Q9HUN5; -.
DR SMR; Q9HUN5; -.
DR STRING; 208964.PA4929; -.
DR PaxDb; 208964-PA4929; -.
DR GeneID; 878645; -.
DR KEGG; pae:PA4929; -.
DR PATRIC; fig|208964.12.peg.5162; -.
DR PseudoCAP; PA4929; -.
DR HOGENOM; CLU_000445_105_4_6; -.
DR InParanoid; Q9HUN5; -.
DR OrthoDB; 5289013at2; -.
DR BioCyc; PAER208964:G1FZ6-5043-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..659
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 680 AA; 75267 MW; CC7F626451C527AF CRC64;
MSNSDVFTGY CLSSAGLANC HHFATFFLYS IHRHLTRPPP EAPGRFIVRH PLALLAVIFL
LLASAVSRAA PEFPAPPASG AWLNGSLDLL EDPDGNLAVE DLEQAEQAGR FVAAAGRTSV
GLSRSAWWLR LDLPRREAVS GGWWLEVASA SLHDLRLYLP DERGGFREHR SGEAVPFAEG
RDHAYRHPLF RIPPGDGPLR VYLRSYDPGG NAFPLRLWSH DELLEYRSQG NLLFGMAYGL
ILALLLYNLF LFTSLRDRAY FWYVLTAASA LVLTLSISGH GFEYFWPERA VPWWLDRLAL
LAIWGICVIR FSQNLLQSRQ HARWAHHLLN ACCLLFLACL AFNAAGWRWQ AAGVLALTLL
ANLPIAIGLA VQRWRQGSAT ARLYLVGFGL VLGSVSLGVM RATALVQPTS ANAMVFPLAL
TLEALLFSLA LASRIQDLKQ ERALALDQAD QEKNARLALL HSAQRDLARA VEVRTNELSE
ANRQLQMREA QLQYAAHHDP LTGLGNRRHL MEFAESALDD ARRHGNSMAL LLIDLDHFKP
INDTHGHDAG DFVLQNVAQR LRHCVRTEDC VARLGGDEFA VLVGGSNAEQ HARDIAERLL
RELAKPVEFA KQWLVITPSI GVALFPGDAL QFGKLYKAAD QALYRVKGAG RAGYAMAADD
ERETAPALPW PTALAPERIS
//
