ID Q9HYU6_PSEAE Unreviewed; 1326 AA.
AC Q9HYU6;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 142.
DE SubName: Full=Probable ATP-dependent helicase {ECO:0000313|EMBL:AAG06685.1};
GN OrderedLocusNames=PA3297 {ECO:0000313|EMBL:AAG06685.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG06685.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG06685.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
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DR EMBL; AE004091; AAG06685.1; -; Genomic_DNA.
DR PIR; H83232; H83232.
DR RefSeq; NP_251987.1; NC_002516.2.
DR RefSeq; WP_003105494.1; NZ_QZGE01000017.1.
DR AlphaFoldDB; Q9HYU6; -.
DR SMR; Q9HYU6; -.
DR STRING; 208964.PA3297; -.
DR PaxDb; 208964-PA3297; -.
DR GeneID; 882460; -.
DR KEGG; pae:PA3297; -.
DR PATRIC; fig|208964.12.peg.3449; -.
DR PseudoCAP; PA3297; -.
DR HOGENOM; CLU_001832_3_2_6; -.
DR InParanoid; Q9HYU6; -.
DR OrthoDB; 9805617at2; -.
DR PhylomeDB; Q9HYU6; -.
DR BioCyc; PAER208964:G1FZ6-3358-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IMP:PseudoCAP.
DR GO; GO:0006364; P:rRNA processing; IMP:PseudoCAP.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:AAG06685.1};
KW Hydrolase {ECO:0000313|EMBL:AAG06685.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 82..245
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 274..451
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1326 AA; 149909 MW; 91E1EBA1F672FBA7 CRC64;
MTDQTPSLDQ LVRRLDQAQI SDRHRLRRQL HELRKQPDDA RLAQWVERFQ TSCAKVEARR
ASVPAIRYDD SLPIAAKRDE IKAAIAAHQV VVIAGETGSG KTTQLPKICL ELGRGIHGLI
GHTQPRRLAA RSVATRVAEE IGTPLGALVG YQVRFEDQSD DSTLVKLMTD GILLAETQHD
RYLERYDTLI VDEAHERSLN IDFLLGYLKT LLHRRPDLKL IITSATIDLE RFSRHFDGAP
VIEVSGRTYP VETWYRPLAA ETDEEGNRVE DDLSVDQGIL AALDEIAAHE REVGKRPGDV
LVFLPGEREI RDAAEMLRKA NLRHTEVLPL YARLTPAEQQ KIFQPRPGRK IVLSTNVAET
SLTVPGIRYV IDSGTARISR YSYRAKVQRL PIEAVSQASA NQRKGRCGRV EPGICVRLYS
EEDFNARPAF TDPEILRTNL AAVILQMLHL RLGDIEAFPF IEPPDGKAIK DGFTLLQELS
AVNREGQLTP LGRQLARLPI DPRLGRMLLE AAQQGSLEEV LTVASALSVQ DPRERPVERQ
QAADQAHAQW KDPDSDFAAL INLWRGFEEQ RQALGSNALR SWCRKNFLNY LRLREWRDAH
RQLTLICREL KLPFGRPAKA EARKPEAKKG ASADNEREVP GIDYAAVHKA ILSGLLSQIG
QKAEEGDYLG ARQRRFWIHP SSGIARKRPQ WIMAAELVET TKLFARMVAK IEPDWLEPLA
GHLIKTNHFE PHWEKRRGQV VAFEQVTLYG LIVIGRRPVH YGPIDPPVAR ELFIREGLVR
GEINSRAKCL SANRQLLEKL DELEAKARRR DILADEETLF AYYDARLPAD IYQTASFEKW
YARERQNQPD LLLMREEDVL AREASEVTAA QYPDRLRLGD LHLSLSYQFE PGTARDGVTV
RVPAPLLPQL PAERIDWLVP GLLYDKAVAL VRNLPKAIRK SFVPVPDFVR AALERITFGE
GSLPQVLGRE LQRMTGVRVA DEAWAEAATQ LDDHLRMNIE VVDAQGKFLG EGRDLAELTA
RFAEASQAAL AIPQADKEQQ RPVEAKAFAS VAEKAQQKVA GLSMTVYPAL VEEQGEVKEG
RFPTQAEADY QHRRALQRLL LQQLAEPAKY LRAKLPGQTE MGLLYRELGR VEALVEDILL
ASLDSCVLQG ESLPRDGAAL AALAERKRAA WNEHAERLAR LVLDILKLWH GLQKRFKGKV
ELAMTVPLND VKGQLANLVY PGFVRATPLE WLKEYPRYLK AIEQRLDKVA GQVQRDRVWS
GELGELWAQY QARLAKHAQE GKRDAELQVY RWMLEEYRVS LFAQQLGTRL PVSDKRLAKQ
WSQVEG
//
