ID Q9HZQ9_PSEAE Unreviewed; 485 AA.
AC Q9HZQ9;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Probable transporter {ECO:0000313|EMBL:AAG06326.1};
GN OrderedLocusNames=PA2938 {ECO:0000313|EMBL:AAG06326.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG06326.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG06326.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AE004091; AAG06326.1; -; Genomic_DNA.
DR PIR; A83278; A83278.
DR RefSeq; NP_251628.1; NC_002516.2.
DR RefSeq; WP_003101463.1; NC_002516.2.
DR AlphaFoldDB; Q9HZQ9; -.
DR SMR; Q9HZQ9; -.
DR STRING; 208964.PA2938; -.
DR PaxDb; 208964-PA2938; -.
DR GeneID; 882791; -.
DR KEGG; pae:PA2938; -.
DR PATRIC; fig|208964.12.peg.3080; -.
DR PseudoCAP; PA2938; -.
DR HOGENOM; CLU_017959_8_2_6; -.
DR InParanoid; Q9HZQ9; -.
DR OrthoDB; 9805749at2; -.
DR PhylomeDB; Q9HZQ9; -.
DR BioCyc; PAER208964:G1FZ6-2988-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0042907; F:xanthine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042906; P:xanthine transport; IBA:GO_Central.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 462..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 50005 MW; 6CDC4B103545CBEE CRC64;
MAYGLQHVLT MYGGIVAVPL ILGQAAGLAP GDIGLLIAAS LFAGGLATLL QTLGVPFFGC
QLPLVQGVSF AGVATMVAII GSGGSGGIPA VLGAVMAASL IGLLITPIFS RITKFFPPLV
TGIVITTIGL TLMPVAARWA MGGNSHAPDF GSMANIGLAA ITLVIVLLLS KLGSASISRL
SILLAMVIGT VIAVFLGMAD FSKVTEGPLV AFPTPFHFGM PTFQVAAIIS MCIVIMVTLV
ETSADILAVG EIIDTKVDSR RLGNGLRADM FSSMLAPIFG SFTQSAFAQN VGLVAVTGIK
SRYVVATGGL FLVILGLLPV MGRVIAAVPT AVLGGAGIVL FGTVAASGIR TLSKVDYRNN
MNLIIVATSI GFGMIPIAAP TFYDHFPSWF ATIFHSGISS SAIMAILLNL AFNHFTAGNS
DQQSVFVAAS ERTLRYQDIA ALHEGDYFLD GKLYDAQGNE VPLAGDDSHG APPRRRSETA
EAGSA
//
