ID Q9I4I9_PSEAE Unreviewed; 393 AA.
AC Q9I4I9;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Probable iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:AAG04535.1};
GN OrderedLocusNames=PA1146 {ECO:0000313|EMBL:AAG04535.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG04535.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG04535.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
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DR EMBL; AE004091; AAG04535.1; -; Genomic_DNA.
DR PIR; A83503; A83503.
DR RefSeq; NP_249837.1; NC_002516.2.
DR RefSeq; WP_003112479.1; NZ_QZGE01000006.1.
DR AlphaFoldDB; Q9I4I9; -.
DR SMR; Q9I4I9; -.
DR STRING; 208964.PA1146; -.
DR PaxDb; 208964-PA1146; -.
DR GeneID; 878737; -.
DR KEGG; pae:PA1146; -.
DR PATRIC; fig|208964.12.peg.1192; -.
DR PseudoCAP; PA1146; -.
DR HOGENOM; CLU_007207_0_0_6; -.
DR InParanoid; Q9I4I9; -.
DR OrthoDB; 9815791at2; -.
DR PhylomeDB; Q9I4I9; -.
DR BioCyc; PAER208964:G1FZ6-1172-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd14861; Fe-ADH-like; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 10..379
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 393 AA; 41888 MW; FE60A3F828D060FD CRC64;
MSDLHYWNYP TDILCGVGAL EQLPRRCALA GARRPLLVTD PGMRALEPLR LVRECLERAG
IDHDLFHELS SNPSLAEVQG GARRFEAGGH DALIALGGGS ALDAAKGIAL LSRDPHGLER
FEWTQTLRSY PTLADYPPLG LPPLLALPTT AGTGSELGRE AVLTDTQLGI KRVVGHRELL
AACVFLDPRL TRGLPPALSA ATGMDALTHH LEALFSPLYH PMSAGIALEG VRLVRQHLEN
AVRDGNDLAA REGMLVASAS AAVAFQKGLG GVHALAHPLG ARHHLHHGLL NAVLLPYVLL
ANRPAIEADA ARLARYLELD EASFDGLLAW ILELRARIGI PANLAALGLD GEDAQWVGEQ
ALADLSSSAT NALPLDARDY ARIYRQAVAG TLA
//
