ID Q9I5N4_PSEAE Unreviewed; 544 AA.
AC Q9I5N4;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=ShlB/FhaC/HecB family hemolysin secretion/activation protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=PA0692 {ECO:0000313|EMBL:AAG04081.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG04081.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG04081.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
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DR EMBL; AE004091; AAG04081.1; -; Genomic_DNA.
DR PIR; C83558; C83558.
DR RefSeq; NP_249383.1; NC_002516.2.
DR RefSeq; WP_003112718.1; NZ_QZGE01000025.1.
DR AlphaFoldDB; Q9I5N4; -.
DR SMR; Q9I5N4; -.
DR STRING; 208964.PA0692; -.
DR TCDB; 1.B.20.3.6; the two-partner secretion (tps) family.
DR PaxDb; 208964-PA0692; -.
DR GeneID; 880708; -.
DR KEGG; pae:PA0692; -.
DR PATRIC; fig|208964.12.peg.725; -.
DR PseudoCAP; PA0692; -.
DR HOGENOM; CLU_037019_0_0_6; -.
DR InParanoid; Q9I5N4; -.
DR OrthoDB; 5664954at2; -.
DR PhylomeDB; Q9I5N4; -.
DR BioCyc; PAER208964:G1FZ6-702-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-KW.
DR GO; GO:0098046; C:type V protein secretion system complex; IMP:PseudoCAP.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0046819; P:protein secretion by the type V secretion system; IMP:PseudoCAP.
DR Gene3D; 3.10.20.310; membrane protein fhac; 1.
DR Gene3D; 2.40.160.50; membrane protein fhac: a member of the omp85/tpsb transporter family; 1.
DR InterPro; IPR005565; Hemolysn_activator_HlyB_C.
DR InterPro; IPR013686; Polypept-transport_assoc_ShlB.
DR PANTHER; PTHR34597:SF1; HEME_HEMOPEXIN TRANSPORTER PROTEIN HUXB; 1.
DR PANTHER; PTHR34597; SLR1661 PROTEIN; 1.
DR Pfam; PF08479; POTRA_2; 1.
DR Pfam; PF03865; ShlB; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Membrane {ECO:0000256|ARBA:ARBA00023237};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..544
FT /note="ShlB/FhaC/HecB family hemolysin secretion/activation
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004331333"
FT DOMAIN 48..121
FT /note="Polypeptide-transport-associated ShlB-type"
FT /evidence="ECO:0000259|Pfam:PF08479"
FT DOMAIN 184..456
FT /note="Haemolysin activator HlyB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03865"
SQ SEQUENCE 544 AA; 59619 MW; 4850048745F99DE7 CRC64;
MKRSLFNCAH PFRQRWSIGC LAVALSCASL ADEAPPAAAG AEPQRLVDIN EYVVRGNTVL
DNRAIEAAVY PFLGPQRSLG DIEGARDALQ AAYQEKGYQS VYVELPEQQV SGGVVYLQVT
ETTIGRVRVV GAKHYSPVEL REEVPALEEG KVPDFAQVQR ELAQVNRTPG RQVLPMVREG
QRPGTMDVDL QVEDKNPWHA SIGLNNDYSA DTRHLRSVVS LGYDNLWQLG HAISLTYFTA
PQDQDNAKVW SGSYTAPLSQ RWSVQLSGYQ SDSDVATVGS MNVVGQGHSY GVAAIYSLPV
TGLWSHSFSF GVDFKDFEEQ TRIGGNNDRV PIKYAPLTLG YNGFRYTERS QLALGLSLVA
GTGSLLGYGD DDEEFDRKRY RAKSGFGVLK GDLNHTLTFG GDWQVATKAA FQLASGPLIS
NEQFAAGGAT SVRGYLAAEN TADDGYLLSQ EWRTPSLGRF LGKRAGGYVN DWRFYVFAEG
AQLRLQDALP EQDDDFSLAS VGIGTRAQLA DWLSGSLDWA FPLLEGTNTD KHDSRLHFSV
QASF
//
