ID Q9IHJ4_9ENTO Unreviewed; 264 AA.
AC Q9IHJ4;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 03-MAY-2023, entry version 84.
DE SubName: Full=RNA-directed RNA polymerase 3D {ECO:0000313|EMBL:AAF35065.1};
DE Flags: Fragment;
OS Poliovirus 1.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Picornaviridae; Ensavirinae; Enterovirus; Enterovirus C.
OX NCBI_TaxID=12080 {ECO:0000313|EMBL:AAF35065.1};
RN [1] {ECO:0000313|EMBL:AAF35065.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=6484CHE95 {ECO:0000313|EMBL:AAF35065.1};
RX PubMed=10906191; DOI=10.1128/JVI.74.16.7381-7390.2000;
RA Gavrilin G.V., Cherkasova E.A., Lipskaya G.Y., Kew O.M., Agol V.I.;
RT "Evolution of circulating wild poliovirus and of vaccine-derived poliovirus
RT in an immunodeficient patient: a unifying model.";
RL J. Virol. 74:7381-7390(2000).
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DR EMBL; AF233161; AAF35065.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 1.20.960.20; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 4.10.880.10; Poliovirus 3D polymerase Domain 1 (Nucleotidyltransferase); 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:AAF35065.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 30..145
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAF35065.1"
FT NON_TER 264
FT /evidence="ECO:0000313|EMBL:AAF35065.1"
SQ SEQUENCE 264 AA; 30414 MW; 04308814CACAD2AA CRC64;
FPRNPGVVTG SAVGCDPDLF WSKIPILMEE KLFAFDYTGY DASLSPAWFE ALKMVLEKIG
FGDRVDYIDY LNHSHHLYKN KTYCVKGGMP SGCSGTSIFN SMINNLIIRT LLLKTYKGID
LDHLKMIAYG DDVIASYPHE VDASLLAQSG KDYGLTMTPA DKSATFEKVT WENVTFLKRF
FRADEKYPFL VHPVMPMKEI HESIRWTKDP RNTQDHVRSL CLLAWHNGEE EYNKFLAKIR
SVPIGRALLL PEYYTLYRRW LDSF
//
