ID Q9J8A8_9ABAC Unreviewed; 523 AA.
AC Q9J8A8;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=Ecdysteroid UDP-glucosyltransferase {ECO:0000256|ARBA:ARBA00013904, ECO:0000256|PIRNR:PIRNR000476};
DE EC=2.4.1.- {ECO:0000256|PIRNR:PIRNR000476};
GN ORFNames=HTSEG24_025 {ECO:0000313|EMBL:CDG72779.1}, HTSEG25_025
GN {ECO:0000313|EMBL:CDG72931.1}, HTSEG26_025
GN {ECO:0000313|EMBL:CDG73068.1}, HTSESP2A_025
GN {ECO:0000313|EMBL:CDG73205.1}, VTSEAL1_025
GN {ECO:0000313|EMBL:CDG72368.1}, VTSEAL2_025
GN {ECO:0000313|EMBL:CDG72505.1}, VTSEOX4_025
GN {ECO:0000313|EMBL:CDG72642.1};
OS Spodoptera exigua multiple nucleopolyhedrovirus.
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=10454 {ECO:0000313|EMBL:AAF33557.1, ECO:0000313|Proteomes:UP000203151};
RN [1] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=1431809;
RA van Strien E.A., Zuidema D., Goldbach R.W., Vlak J.M.;
RT "Nucleotide sequence and transcriptional analysis of the polyhedrin gene of
RT Spodoptera exigua nuclear polyhedrosis virus.";
RL J. Gen. Virol. 73:2813-2821(1992).
RN [2] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=8509757;
RA Zuidema D., van Oers M.M., van Strien E.A., Caballero P.C., Klok E.J.,
RA Goldbach R.W., Vlak J.M.;
RT "Nucleotide sequence and transcriptional analysis of the p10 gene of
RT Spodoptera exigua nuclear polyhedrosis virus.";
RL J. Gen. Virol. 74:1017-1024(1993).
RN [3] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=8811032;
RA van Strien E.A., Jansen B.J., Mans R.M., Zuidema D., Vlak J.M.;
RT "Sequence and transcriptional analysis of the ubiquitin gene cluster in the
RT genome of Spodoptera exigua nucleopolyhedrovirus.";
RL J. Gen. Virol. 77:2311-2319(1996).
RN [4] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9292027;
RA van Strien E.A., Faktor O., Hu Z.H., Zuidema D., Goldbach R.W., Vlak J.M.;
RT "Baculoviruses contain a gene for the large subunit of ribonucleotide
RT reductase.";
RL J. Gen. Virol. 78:2365-2377(1997).
RN [5] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9400958;
RA Heldens J.G., Liu Y., Zuidema D., Goldbach R.W., Vlak J.M.;
RT "Characterization of a putative Spodoptera exigua multicapsid
RT nucleopolyhedrovirus helicase gene.";
RL J. Gen. Virol. 78:3101-3114(1997).
RN [6] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9634102;
RA Broer R., Heldens J.G., van Strien E.A., Zuidema D., Vlak J.M.;
RT "Specificity of multiple homologous genomic regions in Spodoptera exigua
RT nucleopolyhedrovirus DNA replication.";
RL J. Gen. Virol. 79:1563-1572(1998).
RN [7] {ECO:0000313|EMBL:AAF33557.1, ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10567663;
RA IJkel W.F., van Strien E.A., Heldens J.G., Broer R., Zuidema D.,
RA Goldbach R.W., Vlak J.M.;
RT "Sequence and organization of the Spodoptera exigua multicapsid
RT nucleopolyhedrovirus genome.";
RL J. Gen. Virol. 80:3289-3304(1999).
RN [8] {ECO:0000313|Proteomes:UP000203151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10564750; DOI=10.1016/s0168-1702(99)00097-0;
RA Chen X., IJkel W.F., Dominy C., de Andrade Zanotto P.M., Hashimoto Y.,
RA Faktor O., Hayakawa T., Wang C., Prekumar A., Mathavan S., Krell P.J.,
RA Hu Z., Vlak J.M.;
RT "Identification, sequence analysis and phylogeny of the lef-2 gene of
RT Helicoverpa armigera single-nucleocapsid baculovirus.";
RL Virus Res. 65:21-32(1999).
RN [9] {ECO:0000313|EMBL:AAF33557.1}
RP NUCLEOTIDE SEQUENCE.
RA IJkel W.F.J., van Strien E.A., Heldens J.G.M., Broer R., Zuidema D.,
RA Goldbach R.W., Vlak J.M.;
RL Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|Proteomes:UP000069390, ECO:0000313|Proteomes:UP000069454}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HT-SeG24 {ECO:0000313|EMBL:CDG72779.1}, HT-SeG25
RC {ECO:0000313|EMBL:CDG72931.1}, HT-SeG26 {ECO:0000313|EMBL:CDG73068.1},
RC HT-SeSP2A {ECO:0000313|EMBL:CDG73205.1}, VT-SeAl1
RC {ECO:0000313|EMBL:CDG72368.1}, VT-SeAl2 {ECO:0000313|EMBL:CDG72505.1},
RC and VT-SeOx4 {ECO:0000313|EMBL:CDG72642.1};
RX PubMed=24854001; DOI=10.1099/vir.0.064766-0;
RA Theze J., Cabodevilla O., Palma L., Williams T., Caballero P.,
RA Herniou E.A.;
RT "Genomic diversity in European Spodoptera exigua multiple
RT nucleopolyhedrovirus isolates.";
RL J. Gen. Virol. 95:2297-2309(2014).
RN [11] {ECO:0000313|EMBL:QKO28904.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WV103 {ECO:0000313|EMBL:QKO28904.1};
RA Tao P., Yang T., Chen J., Lin C., Hu J., Zhu Y., Lv H., Tian M., Gao Q.,
RA Jia J.;
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the transfer of glucose from UDP-glucose to
CC ecdysteroids which are insect molting hormones.
CC {ECO:0000256|PIRNR:PIRNR000476}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|PIRNR:PIRNR000476,
CC ECO:0000256|RuleBase:RU003718}.
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DR EMBL; AF169823; AAF33557.1; -; Genomic_DNA.
DR EMBL; HG425343; CDG72368.1; -; Genomic_DNA.
DR EMBL; HG425344; CDG72505.1; -; Genomic_DNA.
DR EMBL; HG425345; CDG72642.1; -; Genomic_DNA.
DR EMBL; HG425346; CDG72779.1; -; Genomic_DNA.
DR EMBL; HG425347; CDG72931.1; -; Genomic_DNA.
DR EMBL; HG425348; CDG73068.1; -; Genomic_DNA.
DR EMBL; HG425349; CDG73205.1; -; Genomic_DNA.
DR EMBL; MN481987; QKO28904.1; -; Genomic_DNA.
DR RefSeq; NP_037787.1; NC_002169.1.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR GeneID; 2715779; -.
DR KEGG; vg:2715779; -.
DR OrthoDB; 5462at10239; -.
DR Proteomes; UP000069390; Genome.
DR Proteomes; UP000069454; Genome.
DR Proteomes; UP000069458; Genome.
DR Proteomes; UP000069469; Genome.
DR Proteomes; UP000069541; Genome.
DR Proteomes; UP000069838; Genome.
DR Proteomes; UP000069875; Genome.
DR Proteomes; UP000203151; Genome.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR016224; Ecdysteroid_UDP-Glc_Trfase.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF162; UDP-GLYCOSYLTRANSFERASE FAMILY 305 MEMBER A1, ISOFORM A-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR PIRSF; PIRSF000476; Ecdystd_UDP_glucosyltfrase; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|PIRNR:PIRNR000476};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000476}.
SQ SEQUENCE 523 AA; 59751 MW; BAFDAD2C7256369C CRC64;
MNGCAVLILF FALTTGSAVS AARILAVFPT PAYSHHSVYK VYVRALVERG HEVVVIKSTD
KINYRDLDYR NAGYNMRYNV TEIDASLSQD YFKKLMKQAQ VFRKRGLVAD SSTVTADNYM
GMVRMISDQF NLPAVKRLID EQSKFDLIIA EAFIDYSLVF SHLFDDAPIV QISSGYAVAE
NFETMGAVSR HPVYYPNMWR DKFRDLNVWD LINELYIELK LYNEFNKLVD EQNRLLKQQF
GANTPTIQEL RNRVQLLFVN THPVFDNNRP VPPSVQYLGS LHLTDKHPKS LFGTVREVLD
NATNGVVYVS FGSGISTDEM ESEFIEMLLR TFETLPYTVL WKYDGYLSRI PDNVFVQSWF
EQYDLLHHPN VRAFVTQGGV QSTDEAIDAL VPMVGMPMMG DQAFNTNKYA ELGIGRVVDT
ATVNAFQMIN AITDVAENPS YRKKLAELRH LIRHQAVSPI HKAVWYTEHV INSSKKRDGG
DTLLKTKASN VNYSDYIMSY IFVPLASFTV MNHLRQLLRI NLV
//
