ID Q9KLB6_VIBCH Unreviewed; 324 AA.
AC Q9KLB6;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 126.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:AAF96728.1};
GN OrderedLocusNames=VC_A0830 {ECO:0000313|EMBL:AAF96728.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96728.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF96728.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AE003853; AAF96728.1; -; Genomic_DNA.
DR PIR; G82410; G82410.
DR RefSeq; NP_233216.1; NC_002506.1.
DR AlphaFoldDB; Q9KLB6; -.
DR STRING; 243277.VC_A0830; -.
DR DNASU; 2612695; -.
DR EnsemblBacteria; AAF96728; AAF96728; VC_A0830.
DR KEGG; vch:VC_A0830; -.
DR PATRIC; fig|243277.26.peg.3449; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_39_2_6; -.
DR Proteomes; UP000000584; Chromosome 2.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd08417; PBP2_Nitroaromatics_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR037402; YidZ_PBP2.
DR PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR PANTHER; PTHR30118:SF12; TRANSCRIPTIONAL REGULATOR LYSR FAMILY; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000584}.
FT DOMAIN 28..85
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 324 AA; 36963 MW; 2AE72D0604648075 CRC64;
MIFVPQWYSW LSCSLHRLFM DYIHLSRFSL KHLTALHVML NTRSVTQTAA RLCVSPSSIS
KILAQLRELL NDDLFYRDGN QLIPTPYVQQ MGPTVHHVLS SMNGLLHCTE FDPQAYQGHY
RLAMRESTFE LFAPKVTAIL AACSSELSMT IHSKEHYGFE ALQSGLIDCI LLPHDISQPP
TFAQDLVWQV IESDELVCLM SADHPLAHAE LSVDAYLAYK HIGILDNELN EPYFEKYLTQ
QHETRRIAVA TPDFGAAAIL CRQTHLLLTC SKRWADHAMQ AQGLVQKTLP FEYGKVAYSL
VWNKPSMNDR AIRWLCQQLN SQLT
//
