ID Q9KN49_VIBCH Unreviewed; 869 AA.
AC Q9KN49;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=ClpB protein {ECO:0000313|EMBL:AAF96030.1};
GN OrderedLocusNames=VC_A0116 {ECO:0000313|EMBL:AAF96030.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96030.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF96030.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; AE003853; AAF96030.1; -; Genomic_DNA.
DR PIR; G82499; G82499.
DR RefSeq; NP_232517.1; NC_002506.1.
DR RefSeq; WP_000619136.1; NZ_LT906615.1.
DR AlphaFoldDB; Q9KN49; -.
DR STRING; 243277.VC_A0116; -.
DR TCDB; 3.A.23.1.1; the type vi symbiosis/virulence secretory system (t6ss) family.
DR DNASU; 2612221; -.
DR EnsemblBacteria; AAF96030; AAF96030; VC_A0116.
DR KEGG; vch:VC_A0116; -.
DR PATRIC; fig|243277.26.peg.2757; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_0_6; -.
DR Proteomes; UP000000584; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR017729; ATPase_T6SS_ClpV1.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03345; VI_ClpV1; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF182; CLP ATPASE; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 10..154
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
SQ SEQUENCE 869 AA; 96230 MW; 2190866BA5F72BA1 CRC64;
MIRIELPTLI AKLNAQSKLA LEQAASLCIE RQHPEVTLEY YLDVLLDNPL SDVRLVLKQA
GLEVDQVKQA IASTYSREQV LDTYPAFSPL LVELLQEAWL LSSTELEQAE LRSGAIFLAA
LTRADRYLSF KLISLFEGIN RENLKKHFAM ILSDSAETAV AKTDKNAANP LQAAAETPLG
RFCTNVTEQA RNGELDPVLS RENELNLMVD ILCRRRKNNP IVVGEAGVGK SAMIEGLALR
VVAGKVPTQL QNVELYSLDL GRLQAGASVK GEFEKRLKGV IDAIKQSPKP IILFIDEAHT
LIGSGNQEGG SDAANLLKPA LARGELSTVA ATTWKEYKKY FEKDPALTRR FQLVKLDEPT
IDQAVDILRG LNSVYEKAHN VLITDDALKA AAELSARYIS GRQLPDKAID VLDTACARIA
INMTTPPKRL ALLETLCHQR QLEIDMLERA QFLGQEVDSE RLDVLRNQEL ADEAEKAALT
QSWQQQKSLV ESIIALRAEL MELSQAQEQD PDHLLVVRTA LQEQYQALDA IDHAERLMHP
QVDADQIAEV IADWTGVPVD QMNTDELHKI THLTSILGQA IKGQETAIER IHRHLLTARA
DLRRPGRPKG AFLLVGPSGV GKTETVVQLA EQLYGGKQFL TTINMSEYQE KHTVSRLIGS
PPGYVGYGEG GVLTEAIRKM PYSVVLLDEV EKAHPEVLNI FYQGFDKGEI ADGEGRVIDC
QNIVFFLTSN LGYQTIVDYA DEPAKLDEAL YPELAAFFKP ALLARMEVIP YLPLGKEVLA
QIVRGKLARL EKLFKTRYNA EVVIEESLID EILSRATRSE NGARMLEAII EGQLLPPVSL
ALLNKLAERA PVERIRLAAE AGEFIGEVA
//
