ID Q9L0I3_STRCO Unreviewed; 568 AA.
AC Q9L0I3;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Glycerol phosphate dehydrogenase {ECO:0000313|EMBL:CAB82013.1};
GN OrderedLocusNames=SCO4774 {ECO:0000313|EMBL:CAB82013.1};
GN ORFNames=SCD63.06 {ECO:0000313|EMBL:CAB82013.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB82013.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB82013.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00007330}.
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DR EMBL; AL939121; CAB82013.1; -; Genomic_DNA.
DR RefSeq; NP_628932.1; NC_003888.3.
DR RefSeq; WP_003974200.1; NZ_VNID01000016.1.
DR AlphaFoldDB; Q9L0I3; -.
DR STRING; 100226.gene:17762423; -.
DR PaxDb; 100226-SCO4774; -.
DR PATRIC; fig|100226.15.peg.4847; -.
DR eggNOG; COG0578; Bacteria.
DR HOGENOM; CLU_015740_5_1_11; -.
DR InParanoid; Q9L0I3; -.
DR OrthoDB; 9766796at2; -.
DR PhylomeDB; Q9L0I3; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IBA:GO_Central.
DR GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IBA:GO_Central.
DR Gene3D; 1.10.8.870; Alpha-glycerophosphate oxidase, cap domain; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR031656; DAO_C.
DR InterPro; IPR038299; DAO_C_sf.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000447; G3P_DH_FAD-dep.
DR PANTHER; PTHR11985; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11985:SF15; GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16901; DAO_C; 1.
DR PRINTS; PR01001; FADG3PDH.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00978; FAD_G3PDH_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 24..377
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 404..527
FT /note="Alpha-glycerophosphate oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16901"
FT REGION 538..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 62062 MW; 448EFE3C08517B6E CRC64;
MRTATLGPAQ RAESLAAMAE RELDVLVVGA GVVGAGTALD AVTRGLSVGL VEARDWASGT
SSRSSKLIHG GLRYLEMLDF VLVREALKER GLLLERLAPH LVKPVPFLYP LQHKGWERLY
AGSGVALYDA MSMARGHGRG LPLHRHLSRR HALRVAPALK KDALVGALQY YDAQMDDARF
VATLVRTAAA YGAKVANRAR VTSFLREGER VVGARVQDVE AGGEYEVRAK QVVNATGVWT
DDTQAMVGER GQFHVRASKG IHLVVPKDRI HSSTGLILRT EKSVLFVIPW GRHWIIGTTD
TDWDLDKAHP AASSADIDYL LEHVNSVLSV PLTRDDVEGV YAGLRPLLAG ESDATSKLSR
EHTVAHPVPG LVVVAGGKYT TYRVMAKDAV DEAVHGLDLR VADCVTEETP LLGAEGYHAQ
WNARARIAAR TGLHVVRVEH LLNRYGSLTE ELLELVAADP SLGEPLTGAD DYLRAEVVYA
ASHEGARHLD DVLTRRTRIS IETFDRGTRC AREAAELMAP VLGWDKGQVE REIEHYEKRV
EAERESQRQP DDLTADAARL GAPDIAAR
//
