ID Q9L2J6_STRCO Unreviewed; 310 AA.
AC Q9L2J6;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=cutinase {ECO:0000256|ARBA:ARBA00013095};
DE EC=3.1.1.74 {ECO:0000256|ARBA:ARBA00013095};
GN Name=lipA {ECO:0000313|EMBL:CAB69685.1};
GN OrderedLocusNames=SCO0713 {ECO:0000313|EMBL:CAB69685.1};
GN ORFNames=SCF42.23c {ECO:0000313|EMBL:CAB69685.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB69685.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB69685.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=cutin + H2O = cutin monomers.; EC=3.1.1.74;
CC Evidence={ECO:0000256|ARBA:ARBA00034045};
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily.
CC {ECO:0000256|ARBA:ARBA00008645}.
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DR EMBL; AL939106; CAB69685.1; -; Genomic_DNA.
DR RefSeq; NP_625018.1; NC_003888.3.
DR RefSeq; WP_003978149.1; NZ_VNID01000004.1.
DR AlphaFoldDB; Q9L2J6; -.
DR SMR; Q9L2J6; -.
DR STRING; 100226.gene:17758296; -.
DR ESTHER; strco-LIPA; Polyesterase-lipase-cutinase.
DR PaxDb; 100226-SCO0713; -.
DR PATRIC; fig|100226.15.peg.701; -.
DR eggNOG; COG1073; Bacteria.
DR HOGENOM; CLU_052605_1_0_11; -.
DR InParanoid; Q9L2J6; -.
DR OrthoDB; 1466228at2; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR22946:SF9; POLYKETIDE TRANSFERASE AF380; 1.
DR PANTHER; PTHR22946; UNCHARACTERIZED; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
SQ SEQUENCE 310 AA; 32665 MW; 7633C4DF33B5EAFA CRC64;
MQQNPHTHAA PGAARPVLRG VRRRLAAVTA AVAAVLVLGT LTGPGAQAAD NPYERGPAPT
ESSIEALRGP YSVADTSVSS LAVTGFGGGT IYYPTSTSDG TFGAVVIAPG FTAYQSSIAW
LGPRLASQGF VVFTIDTNTT LDQPDSRGRQ LLAALDYLTG RSSVRGRIDS GRLGVMGHSM
GGGGTLEAAK SRPSLQAAIP LTPWNLDKSW PEVSTPTLVV GADGDTIAPV ASHAEPFYSG
LPSSTDRAYL ELNNATHFSP NTSNTTIAKY SISWLKRFID DDTRYEQFLC PLPRPSLTIE
EYRGNCPHGS
//
