ID Q9M197_ARATH Unreviewed; 1272 AA.
AC Q9M197;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Copia-type reverse transcriptase-like protein {ECO:0000313|EMBL:CAB75469.1};
GN Name=T16L24.270 {ECO:0000313|EMBL:CAB75469.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:CAB75469.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RG European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG Institute for Genomic Research;
RG Kazusa DNA Research Institute;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2] {ECO:0000313|EMBL:CAB75469.1}
RP NUCLEOTIDE SEQUENCE.
RA D'Angelo M., Vezzi A., Modesto D., Pigazzi M., Valle G., Mewes H.W.,
RA Lemcke K., Mayer K.F.X., Quetier F., Salanoubat M.;
RL Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAB75469.1}
RP NUCLEOTIDE SEQUENCE.
RA EU Arabidopsis sequencing project;
RL Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AL138659; CAB75469.1; -; Genomic_DNA.
DR PIR; T49313; T49313.
DR AlphaFoldDB; Q9M197; -.
DR ExpressionAtlas; Q9M197; differential.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR025314; DUF4219.
DR InterPro; IPR025724; GAG-pre-integrase_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR42648:SF22; RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON TNT 1-94; 1.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR Pfam; PF13961; DUF4219; 1.
DR Pfam; PF13976; gag_pre-integrs; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF07727; RVT_2; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Nucleotidyltransferase {ECO:0000313|EMBL:CAB75469.1};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:CAB75469.1};
KW Transferase {ECO:0000313|EMBL:CAB75469.1};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 280..295
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 522..688
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 219..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 187..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 250..276
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..784
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1272 AA; 146951 MW; BCE4F92858FD3440 CRC64;
MASNNVPFQV PVLTKSNYDN WSLRMKAILG AHDVWEIVEK GFIEPENEGS LSQTQKDGLR
DSRKRDKKAL CLIYQGLDED TFEKVVEATS AKEAWEKLRT SYKGADQVKK VRLQTLRGEF
EALQMKEGEL VSDYFSRVLT VTNNLKRNGE KLDDVRIMEK VLRSLDLKFE HIVTVIEETK
DLEAMTIEQL LGSLQAYEEK KKKKEDIVEQ VLNMQITKEE NGQSYQRRGG GQVRGRGRGG
YGNGRGWRPH EDNTNQRGEN SSRGRGKGHP KSRYDKSSVK CYNCGKFGHY ASECKAPSNK
KFKEKANYVE EKIQEEDMLL MASYKKDEQE ENHKWYLDSG ASNHMCGRKS MFAELDESVR
GNVALGDESK MEVKGKGNIL IRLKNGDHQF ISNVYYIPSM KTNILSLGQL LEKGYDIRLK
DNNLSIRDKE SNLITKVPMS KNRMFVLNIR NDIAQCLKMC YKEESWLWHL RFGHLNFGGL
ELLSRKEMVR GLPCINHPNQ VCEGCLLGNQ FKMSFPKESS SRAQKPLELI HTDVCGPIKP
KSLGKSNYFL LFIDDFSRKT WVYFLKEKSE VFEIFKKFKA HVEKESGLVI KTMRSDSGGE
FTSKEFLKYC EDNGIRRQLT VPRSPQQNGV AERKNRTILE MARSMLKSKR LPKELWAEAV
ACAVYLLNRS PTKSVSGKTP QEAWSGRKPG VSHLRVFGSI AHAHVPDEKR NKLDDKSEKY
IFIGYDNNSK GYKLYNPDTK KTIISRNIVF DEEGEWDWNS NEEDYNFFPH FEEDKPEPTR
EEPPSEEPTT PPTSPTSSQI EESSSERTPR FRSIQELYEV TENQENLTLF CLFAECEPMD
FQEAIEKKTW RNAMDEEIKS IQKNDTWELT SLPNGHKAIG VKWVYKAKKN SKGEVERYKA
RLVAKGYSQR AGIDYDEIFA PVARLETVRL IISLAAQNKW KIHQMDVKSA FLNGDLEEEV
YIEQPQGYIV KGEEDKVLRL KKVLYGLKQA PRAWNTRIDK YFKEKDFIKC PYEHALYIKI
QKEDILIACL YVDDLIFTGN NPSMFEEFKK EMTKEFEMTD IGLMSYYLGI EVKQEDNGIF
ITQEGYAKEV LKKFKMDDSN PSLVGSLRYL TCTRPDILYA VGVVSRYMEH PTTTHFKAAK
RILRYIKGTV NFGLHYSTTS DYKLVVCHAI WLRNLLKELS LPQEEPTKIF VDNKSAIALA
KNPVFHDRSK HIDTRYHYIR ECVSKKDVQL EYVKTHDQVA DIFTKPLKRE DFIKMRSLLG
VAKSSLRGGV ES
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