ID FB304_ARATH Reviewed; 1378 AA.
AC Q9M1I1; Q56XJ3;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 151.
DE RecName: Full=F-box protein At3g54460;
GN OrderedLocusNames=At3g54460; ORFNames=T14E10.30;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=24265739; DOI=10.1371/journal.pone.0078982;
RA Xu R., Zhang S., Huang J., Zheng C.;
RT "Genome-wide comparative in silico analysis of the RNA helicase gene family
RT in Zea mays and Glycine max: a comparison with Arabidopsis and Oryza
RT sativa.";
RL PLoS ONE 8:E78982-E78982(2013).
CC -!- SIMILARITY: Belongs to the helicase family. {ECO:0000305}.
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DR EMBL; AL138656; CAB77566.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79234.1; -; Genomic_DNA.
DR EMBL; AY091046; AAM13867.1; -; mRNA.
DR EMBL; BT004336; AAO42330.1; -; mRNA.
DR EMBL; AK221681; BAD95377.1; -; mRNA.
DR EMBL; AK227150; BAE99194.1; -; mRNA.
DR PIR; T47605; T47605.
DR RefSeq; NP_680129.1; NM_148874.5.
DR AlphaFoldDB; Q9M1I1; -.
DR BioGRID; 9927; 1.
DR STRING; 3702.Q9M1I1; -.
DR iPTMnet; Q9M1I1; -.
DR MetOSite; Q9M1I1; -.
DR PaxDb; 3702-AT3G54460-1; -.
DR ProteomicsDB; 230080; -.
DR EnsemblPlants; AT3G54460.1; AT3G54460.1; AT3G54460.
DR GeneID; 824611; -.
DR Gramene; AT3G54460.1; AT3G54460.1; AT3G54460.
DR KEGG; ath:AT3G54460; -.
DR Araport; AT3G54460; -.
DR TAIR; AT3G54460; -.
DR eggNOG; KOG0298; Eukaryota.
DR eggNOG; KOG1001; Eukaryota.
DR HOGENOM; CLU_006077_0_0_1; -.
DR InParanoid; Q9M1I1; -.
DR OrthoDB; 101644at2759; -.
DR PhylomeDB; Q9M1I1; -.
DR PRO; PR:Q9M1I1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M1I1; baseline and differential.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18008; DEXDc_SHPRH-like; 1.
DR CDD; cd09917; F-box_SF; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR011124; Znf_CW.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45626:SF14; ATP-DEPENDENT DNA HELICASE (EUROFUNG); 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51050; ZF_CW; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Helicase; Hydrolase; Metal-binding; Nucleotide-binding;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..1378
FT /note="F-box protein At3g54460"
FT /id="PRO_0000283570"
FT DOMAIN 282..328
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT DOMAIN 720..885
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 1185..1324
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT ZN_FING 571..622
FT /note="CW-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00454"
FT REGION 65..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 834..837
FT /note="DEAH box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT COMPBIAS 69..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 580
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00454"
FT BINDING 583
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00454"
FT BINDING 603
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00454"
FT BINDING 614
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00454"
FT BINDING 733..740
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 1378 AA; 155413 MW; 5DB6CA2B3FF11CB9 CRC64;
MADDHKLCGF LCTVLSVDSP DLLQSGSSCF IFNDGSVTGF KSENGLILSL TNPISNLQSL
ISSKGDHDVE NSGTIEDGRL ETPQKRRKCV EGESSGKRKT PKSKRRVLSG SKEKTVQGRK
RVKSIGMVNG SISVVQQLHA LVANKCLKII CRVVKVDKGE NGEERAVVLV DVYLPIELWS
GWQFPKSQAT AAALFKHLSC DWGLRVSILD GKSIWEEANG RIKAIWDLSD CHVFDCKLLC
NAPNSPKRRL FKLHEIFKSL PSPGNHDVSY SSRVLPSTDS CVSGVWDLSD DVLISILMKL
DTKDLFSIAA VCRLFRSLTS LIVPCMNLKL FPHQQAAVGW MLERERKAEV SSHPLYLSFD
TEDGFSFYVN AVTGDIITEA APMVKDFRGG MFCDEPGLGK TITALSLILK TQGTMADPPE
GLPIVWCTHK SDKKCAYYEY TSDQFTSNSM SAVKRFQSPS SCRNQVSFEA FRPLLESKSL
PFKQARLMDP DDQTLESKNS NFENEFETHI PASLDLKAQC RKSLGNVRKN LLPAYNGASE
LSEVMEAKRI SNWKKCGMIT GCKRKGLTDS DVESDIWMQC DSCSKWRRII DEGVSVTGSA
WFCSNNNDPA YQSCNDPEEL WDKSQPIKYL QGFYTKGASG EESDNISFFT SVLREHKSSV
SSTVKKALIW LAKLPLEKLS QMETVGLPGP VLGLKLDALG FQRIFRAFGL KSRVEKGVTK
WFYPKFLENL VFDVPALKVA LCQPLDTFRL YLSKATLIVV PTNLVNHWLT QIQKHVCSDQ
LRILVWADHI ELSPHSLAWD YDVVITTFSR LSAEWNPRKK SPLIQVHWLR VMLDEGHTLG
SSVSLTNKFQ MAVSLTACNR WLLTGTPTPN TPNSQLSHIQ PLLKFLHEEV YGENPKFWEA
GILRPFEAEM EEGRLRLLQL LQRCMISSRK KDLQMIPPCI KKVTYLNFLP GHARSYNELV
ETVRRNILLA DWNDPSHVES LLNSKQWKFR SITISNVRLS CCVAGHIKMT DAGHDIKETM
DALLENDLDL WTEEYSFIQD SLIGGCNCKR CGEWCRLPVI TPCRHLLCLD CVALDSERCT
ISGCGYLYEM QTPETLARPE NPNPKWPVPK DLIELQPSYK QDDWNPDWQS TSSSKVSYLV
DRLRKLHEGN KKSILSFNKT DNDNLEDNPP GTSEAFLGKE LHGQDCGSQM VFVDKVLIFS
QFLEHIHVIE QQLTTAGIKF GKMYSPMQSY NKMKALAMFQ NDADCMALLM DGSGALGLDL
SFVTHVFLME PIWDKSLEEQ VISRAHRMGA KRPIFVETLT MRGTIEEQMM RFLEDAEKSD
RLLSGDYIEA KQETTRSRRT LHDLVESNYL SHLSFVRSDG KMEFAASQLA GLKDHQLA
//
