ID   Q9P978_NEUCS            Unreviewed;       834 AA.
AC   Q9P978;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Rad54 homolog {ECO:0000313|EMBL:BAA93079.1};
GN   Name=mus-25 {ECO:0000313|EMBL:BAA93079.1};
OS   Neurospora crassa.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=5141 {ECO:0000313|EMBL:BAA93079.1};
RN   [1] {ECO:0000313|EMBL:BAA93079.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=OR {ECO:0000313|EMBL:BAA93079.1};
RA   Handa N., Noguchi Y., Sakuraba Y., Ballario P., Macino G., Fujimoto N.,
RA   Ishii C., Inoue H.;
RT   "Characterization of the Neurospora crassa mus-25 mutant: the gene encodes
RT   a protein which is homologous to Saccharomyces cerevisiae Rad54 belonging
RT   to the Snf2p/Swi2p subfamily.";
RL   Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AB032901; BAA93079.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9P978; -.
DR   VEuPathDB; FungiDB:NCU02348; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.20.120.850; SWI2/SNF2 ATPases, N-terminal domain; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013967; Rad54_N.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR   PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF08658; Rad54_N; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          242..420
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          575..728
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          790..810
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   834 AA;  93508 MW;  2B7B8FF4ED9A8DFC CRC64;
     MSASMVSTPK AASKDNSTNS LALTQRSKFP TPQSLDKLTK PFKCPGSATR TVAVDRPARK
     RRKIDYKGAG GEDDEDGADK PYTNADRLAL ANRDANKFPV FAVKDKSQVF RKAFSVPLIN
     KNTTAYNPNR PPPTLGLRQG AVFVAKPLHD PCDEFAIVLY DPTVDDKPKD TAPEAIEEKK
     EEPEVKVDAP LVHKSLAEIL GIKKKVEGEH PRVPVVIDPR LAKVLRPHQI EGVRFMYRCV
     TGMIDEKANG CIMADEMGLG KTLQCITLLW TLLKQSPDAG KSTIQKAIVA CPSSLVRNWA
     NELVKWLGAD AITPFAIDGK ASKEELTRQL RQWAIASGRS VTRPVIIVSY ETLRLNVDEL
     KGTPIGLMLC DEGHRLKNGD SQTFSALNSL NVSRRVILSG TPIQNDLSEY FALITVANPD
     LLGTRLEFRK RFEIPILRGR HADASEAERK RGDECLVELL AIVNKFIIRR TNDILSKYLP
     VKYEHVVFCN LAPFQLDLYN YFVASPDIQA LLRGKGSQPL KAINILKKLC NHPDLLDLSA
     DLPGCEQYWP EDYVPKEARG RDRDVKPWYS GKMQVLDRML ARIRADTNDK IVLISNYTQT
     LDLFERLCRN RQYGCLRLDG TMNVNKRQKL VDKFNDPEGD EFVFLLSSKA GGCGLNLIGA
     NRLVLFDPDW NPAADQQALA RVWRDGQKKD CFVYRFIATG TIEEKIFQRQ SHKQSLSSCV
     VDSAEDVERH FSLDSRELFT YRPGTKSDTH DTFKCKRCKP DGRQYMKAQA MLYGDTSTWN
     HFVNHWEGED AAGKSGKGGD PNGGSGGMKS IHDHLLRQEV GERDVSAVFQ YISH
//