ID Q9R859_LISMN Unreviewed; 499 AA.
AC Q9R859;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 143.
DE SubName: Full=Internalin E {ECO:0000313|EMBL:CAA07458.1};
GN Name=inlE {ECO:0000313|EMBL:CAA07458.1};
OS Listeria monocytogenes.
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=1639 {ECO:0000313|EMBL:CAA07458.1};
RN [1] {ECO:0000313|EMBL:CAA07458.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EGD {ECO:0000313|EMBL:CAA07458.1};
RX PubMed=9862466; DOI=10.1007/s004380050880;
RA Raffelsbauer D., Bubert A., Engelbrecht F., Scheinpflug J., Simm A.,
RA Hess J., Kaufmann S.H., Goebel W.;
RT "The gene cluster inlC2DE of Listeria monocytogenes contains additional new
RT internalin genes and is important for virulence in mice.";
RL Mol. Gen. Genet. 260:144-158(1998).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the internalin family.
CC {ECO:0000256|ARBA:ARBA00009432}.
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DR EMBL; AJ007319; CAA07458.1; -; Genomic_DNA.
DR PIR; AI1107; AI1107.
DR RefSeq; WP_010989387.1; NZ_RQRK01000006.1.
DR AlphaFoldDB; Q9R859; -.
DR PATRIC; fig|1639.768.peg.66; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1220; -; 1.
DR Gene3D; 1.10.8.390; Internalin N-terminal Cap domain-like; 1.
DR Gene3D; 2.60.40.4270; Listeria-Bacteroides repeat domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR012569; Inl_IR.
DR InterPro; IPR013378; InlB-like_B-rpt.
DR InterPro; IPR024634; Internalin_N.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR042229; Listeria/Bacterioides_rpt_sf.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR032675; LRR_dom_sf.
DR NCBIfam; TIGR02543; List_Bact_rpt; 1.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF09479; Flg_new; 1.
DR Pfam; PF12354; Internalin_N; 1.
DR Pfam; PF12799; LRR_4; 3.
DR Pfam; PF08191; LRR_adjacent; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR PROSITE; PS51450; LRR; 4.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 473..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 466..499
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 412..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 53941 MW; C63461847594C7CA CRC64;
MKRNKTALRI LVTLAVVLAI TFWVGMSSKE VQAAVIEHPT PINEIFTDPV LTDNVKTLLG
KADVTDEVTQ TDLDSVTHLS AKSAGITTIE GLQYLTNLSE LELIDNQVTD LNPLTNLTKI
TELRLSGNPL KDVSALAGLK NLKTMDLIYT DITDVTPLAG LSNLQVLNLD INQITDITPL
AGLSNLQFLS FGSTQVSDLT PLANLSKLTT LNAMNSKVSD VSPLTGLSNL TEVYLEENQI
SDVSPLAKLP NLSIVTLTNQ TITNQPVFYQ NKPIVPNVVT GLSGELIAPD TISDNGTYTS
PNLTWDLNSF INSVSYTFNQ SVTFKNTTAP FSGTVTQPLT EVYAVVFDVD GEQTSAMVGV
NELINEPTAP AKEGYIFDGW YDAKTDGNKW DFGIDKMPAS DITLYAKFTE NEEPNASSPI
NVEPNDNNSD NAEPNASSSN NVQENGTNEG INNLNSSGED KVNIKLPITG DKLNVLPIFV
GAVLIGIGLV LFRKKRQTK
//
