ID   Q9RDX5_LEGPN            Unreviewed;       338 AA.
AC   Q9RDX5;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   13-SEP-2023, entry version 49.
DE   SubName: Full=N-acetylneuraminic acid condensing enzyme {ECO:0000313|EMBL:CAB65212.1};
GN   Name=neuB {ECO:0000313|EMBL:CAB65212.1};
OS   Legionella pneumophila.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=446 {ECO:0000313|EMBL:CAB65212.1};
RN   [1] {ECO:0000313|EMBL:CAB65212.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=RC1 {ECO:0000313|EMBL:CAB65212.1};
RA   Lueneberg E.;
RT   "Cloning and functional characterization of a 30 kb gene locus required for
RT   lipopolysaccharide biosynthesis in Legionella pneumophila.";
RL   Zentralbl. Bakteriol. 290:37-49(2000).
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DR   EMBL; AJ007311; CAB65212.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9RDX5; -.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR020007; N-AcNeuraminate_synthase.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   NCBIfam; TIGR03569; NeuB_NnaB; 1.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
FT   DOMAIN          283..338
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   338 AA;  37026 MW;  421A90117FA3050D CRC64;
     MTCFIIAEAG VNHNGDLQLA KELVYAAKES GADAVKFQTF KADTLVNKTV EKAEYQKNNA
     PESSTQYEML KALELSEEDH YLLSELANSL GIEFMSTGFD EQSIDFLISL GVKRLKIPSG
     EITNVPYLQH CASKKLPLII STGMCDLQEV RVAIDTVKPY YGNSLSDYLV LLHCTSNYPA
     SYQDVNLKAM QTLADEFQLP VGYSDHTLGI LVPTLAVGMG ACVIEKHFTM DKSLPGPDHL
     ASMDPEEMKN LVQSIRDAET VLGSGEKKPS DNELPIRALV RRSITLRRDL VKGAQISKED
     LILLRPGTGI APSEISNIVG SRLSMNLSAG TNFVMGTY
//