ID Q9S241_STRCO Unreviewed; 747 AA.
AC Q9S241;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:CAB46809.1};
GN OrderedLocusNames=SCO1711 {ECO:0000313|EMBL:CAB46809.1};
GN ORFNames=SCI30A.32c {ECO:0000313|EMBL:CAB46809.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB46809.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB46809.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; AL939110; CAB46809.1; -; Genomic_DNA.
DR PIR; T36812; T36812.
DR RefSeq; NP_625985.1; NC_003888.3.
DR RefSeq; WP_011027934.1; NZ_VNID01000018.1.
DR AlphaFoldDB; Q9S241; -.
DR STRING; 100226.gene:17759305; -.
DR PaxDb; 100226-SCO1711; -.
DR PATRIC; fig|100226.15.peg.1729; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_3_11; -.
DR InParanoid; Q9S241; -.
DR OrthoDB; 7376058at2; -.
DR PhylomeDB; Q9S241; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02782; MopB_CT_1; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 2..58
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 747 AA; 78322 MW; 6D2C3A09B5F0E180 CRC64;
MPRTALRICP LCEATCGLAL TVDGSTVTAA RGDRDDVFSR GFICPKGASF GAVDSDPDRL
RAPLVRTNGE LREATWEEAF DAVAAGVRPL VERYGPHSVG VVLGNPNVHT MAGALYPNVL
LGALGSRSLF TASTLDQMPK HVSSGLLFGD ANAIPVPDLD RTDHLLLIGA NPLESNGSLC
TAPDFPGRLR ALKARGGTLT VVDPRRTRTA KLADRHVAIR PGSDALLLAA MAHVLYEEGL
VDLGALAPHV GGVDDVAAAV RDFTPESVAA ACDVDADVTR ALARELAAAP TAAVYGRIGS
CTVPHGTIAS WLVDVLNILT GNLDRPGGAL FPQAATDRTP RPAGPGRGFA LGRWRSRVSG
HPEAKGELPL SALAEEIDTA TDAGEPVRAL LTIAANPVLS APDGDRLDKA LESLDFMVSV
DPYLNETSRH AHVVLPPPPP AQSPHHDFAF NTLAVRNQVR YTRPAVPLEP GRMAETEILA
RLTLAVTGAH GTDPAAVDAL VIEQTLAKAV REPHSPAHGR DPAELTALLT GETGPERRLD
LMLRLGPYGD GFGARPDGLT LERLLAHPHG IDLGPLRPRL PQPLKTRSGK VELLPAPIAA
DLPRLARARD ARPAGLVLVG RRHLRSNNSW MHNVPALTGG SNRCTLHVHP EDAARLGLRG
AQPVRVTGPG GAVTAPAEVT DAVRPGVVSL PHGWGHDRPG TRQTHAATDP GVNVNQLLDG
SALDPLSGNA VLNGVPVTLT PLTGAEL
//
