ID Q9TYD1_PLAFA Unreviewed; 559 AA.
AC Q9TYD1;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 22-FEB-2023, entry version 51.
DE SubName: Full=Thrombospondin-related protein {ECO:0000313|EMBL:BAA31180.1};
DE Flags: Fragment;
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:BAA31180.1};
RN [1] {ECO:0000313|EMBL:BAA31180.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9657338; DOI=10.1016/S0166-6851(98)00004-8;
RA Jongwutiwes S., Putaporntip C., Kanbara H., Tanabe K.;
RT "Variation in the thrombospondin-related adhesive protein (TRAP) gene of
RT Plasmodium falciparum from Thai field isolates.";
RL Mol. Biochem. Parasitol. 92:349-353(1998).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB006344; BAA31180.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9TYD1; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01471; vWA_micronemal_protein; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR PANTHER; PTHR16059:SF25; THROMBOSPONDIN-RELATED ANONYMOUS PROTEIN; 1.
DR Pfam; PF00090; TSP_1; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00209; TSP1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50092; TSP1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..559
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004333996"
FT DOMAIN 48..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 280..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 559
FT /evidence="ECO:0000313|EMBL:BAA31180.1"
SQ SEQUENCE 559 AA; 63412 MW; 9C27C6E9A2A2A83F CRC64;
MNHLGNVKYL VIVFLIFFDL FLVNGRDVQN NIVDEIKYRE EVCNDEVDLY LLMDCSGSYR
RHNWVNHAVP LAMKLIQQLN LNENAIHLYL NDFSNNAREI IRLHSDASKN KEKALIIIKS
LLNTNLPYGR TNLSDALLQV RKHLNDRINR ENANQLVVIL TDGIPDSIQD SLKESRKLND
RGVKIAVFGI GQGINVAFNR FLVGCHPSDG KCNLYADSAW ENVKNVIGPF MKAVCVEVEK
TASCGVWDEW SPCSVTCGKG TRSRKREILH EGCTSELQEQ CEEERCPPKW EPLDVPHEPE
DDQPRPRGDN FAVEKPEENI IDNNPQEPSP NPEEGKGENP KGFDLDENPE NPPNPDIPQQ
EPNIPEDSEK EVPSDVPKNP EDDREENFDI PKKPENKHDN QNNLPNDKSD RSIPYSPLPP
KVLDNERKQS DPQSQDNNGN RHVPNSEDRE TRPHGRNNEN RSYNRKYNDT PKHPEREEHE
KPDNNKKKGG SDNKYKIAGG IAGGLALLAS AGLAYKFVVP GAATPYAGEP APFDETLGEE
DKDLDEPEQF RLPEENEWN
//
