ID Q9U1W0_CAEEL Unreviewed; 579 AA.
AC Q9U1W0;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 24-JAN-2024, entry version 156.
DE SubName: Full=J domain-containing protein {ECO:0000313|EMBL:CAB63399.1};
GN Name=dnj-29 {ECO:0000313|EMBL:CAB63399.1,
GN ECO:0000313|WormBase:Y63D3A.6a};
GN ORFNames=CELE_Y63D3A.6 {ECO:0000313|EMBL:CAB63399.1}, Y63D3A.6
GN {ECO:0000313|WormBase:Y63D3A.6a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB63399.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB63399.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB63399.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BX284601; CAB63399.1; -; Genomic_DNA.
DR RefSeq; NP_493464.1; NM_061063.3.
DR AlphaFoldDB; Q9U1W0; -.
DR SMR; Q9U1W0; -.
DR PeptideAtlas; Q9U1W0; -.
DR EnsemblMetazoa; Y63D3A.6a.1; Y63D3A.6a.1; WBGene00001047.
DR GeneID; 173278; -.
DR UCSC; Y63D3A.6b; c. elegans.
DR AGR; WB:WBGene00001047; -.
DR WormBase; Y63D3A.6a; CE20337; WBGene00001047; dnj-29.
DR GeneTree; ENSGT00390000001965; -.
DR HOGENOM; CLU_014210_1_0_1; -.
DR OrthoDB; 1605at2759; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00001047; Expressed in embryo and 4 other cell types or tissues.
DR ExpressionAtlas; Q9U1W0; baseline and differential.
DR GO; GO:0031207; C:Sec62/Sec63 complex; IBA:GO_Central.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006620; P:post-translational protein targeting to endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Proteomics identification {ECO:0007829|EPD:Q9U1W0,
KW ECO:0007829|PeptideAtlas:Q9U1W0};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 107..168
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 496..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..511
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..541
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 66876 MW; 0698C986FE4C3333 CRC64;
MGRASFEYDE VGNTFYYVLV AFYAIILFPA TYLCLPGASK PEPEHVINEH ECQCDGCDKK
RRQKAANKPW RRTKKIITIV VLVVAWAIFA IIVKKTTEIE QTHKDYDPYQ ILGLDQGADE
KAIKKAWRDM SKIHHPDRGG DAQFFDKIAK AHQALTDKEA RENWEKYGNP DGPTATTFGI
ALPKWLVSKE YGLWVLAFYG LIFMIILPVS VGMWWYSSIK YSADKVLLDT TRMYYYFINR
TPRMEIGRMI AVLSGSFEFS KQYNKEIQER ETDDYEVPRL MKQIAGVNDK GKEQPLSQPY
ALKSRVLLHA YLSRLPLESQ NDALEEDQSY IITRILRFVE EMVNCSQNLM NYSQHTKISI
ETFDNLLKLQ PMFVQALWQK NSPLLQLPHI TDYNLQHLRK KRVFSCHDLA VMDAETRRSV
LRSLSNEEYR DVMVVLSMMP RLQIETKTVV EGEDDKHELT AGCVVTLKVT MRRSRLIDPQ
EAGLADQYKK YAEDGGDDEL EASEAPEEAA ATVEEEEVKK RKPWEKNKPK QKKKKAQGQG
QKKFVKKNAP ASPDTEKALK EEAKVLREEI WTIFAKKIS
//
