ID Q9U786_DROME Unreviewed; 266 AA.
AC Q9U786;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 22-FEB-2023, entry version 90.
DE SubName: Full=Drep3 {ECO:0000313|EMBL:AAF03219.1};
GN Name=Drep3 {ECO:0000313|FlyBase:FBgn0028407};
GN Synonyms=Drep-3 {ECO:0000313|FlyBase:FBgn0028407}, drep3
GN {ECO:0000313|EMBL:AAF03219.1}, Rep3 {ECO:0000313|FlyBase:FBgn0028407};
GN ORFNames=CG8364 {ECO:0000313|FlyBase:FBgn0028407};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF03219.1};
RN [1] {ECO:0000313|EMBL:AAF03219.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10627165; DOI=10.1038/sj.cdd.4400570;
RA Inohara N., Nunez G.;
RT "Genes with homology to DFF/CIDEs found in Drosophila melanogaster.";
RL Cell Death Differ. 6:823-824(1999).
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DR EMBL; AF149796; AAF03219.1; -; mRNA.
DR AlphaFoldDB; Q9U786; -.
DR UCSC; CG8364-RB; d. melanogaster.
DR AGR; FB:FBgn0028407; -.
DR FlyBase; FBgn0028407; Drep3.
DR VEuPathDB; VectorBase:FBgn0028407; -.
DR HOGENOM; CLU_1070656_0_0_1; -.
DR ExpressionAtlas; Q9U786; baseline and differential.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-UniRule.
DR GO; GO:0042981; P:regulation of apoptotic process; IBA:GO_Central.
DR CDD; cd01615; CIDE_N; 1.
DR Gene3D; 3.10.20.10; -; 1.
DR InterPro; IPR003508; CIDE-N_dom.
DR PANTHER; PTHR12306; CELL DEATH ACTIVATOR CIDE; 1.
DR PANTHER; PTHR12306:SF15; DNAATION FACTOR-RELATED PROTEIN 1, ISOFORM B-RELATED; 1.
DR Pfam; PF02017; CIDE-N; 1.
DR SMART; SM00266; CAD; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR PROSITE; PS51135; CIDE_N; 1.
PE 2: Evidence at transcript level;
KW Apoptosis {ECO:0000256|PROSITE-ProRule:PRU00447}.
FT DOMAIN 117..192
FT /note="CIDE-N"
FT /evidence="ECO:0000259|PROSITE:PS51135"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 224..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..83
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 266 AA; 29414 MW; 5A9975BCA8AFA645 CRC64;
MTAMNADETK LAGMPPGAEE EQEPEREQKK ESDGAAAAAG VQCDPDSRIV APPPRQRTLT
RTAELDADCE DIELDADDGL DDAADDITLE LALSPHSSAT PTPSPTTADE DFAQLDNSKP
FKIKDITRNI RKAVVATTLS ELRTKVSLKF ERAQRRLHLD CDGTEVDDEE YFSTLEPNAE
LIAVFPGEQW RDPSDYNANL RRTSLDAQRL RSLVSKLQPN YMNDDDLDKL SNMDPNSLVD
ITGREPKDNE YSARSDAARL STELSC
//
