ID Q9XZK0_TRYCR Unreviewed; 221 AA.
AC Q9XZK0;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 24-JAN-2024, entry version 95.
DE SubName: Full=GTP-binding protein {ECO:0000313|EMBL:AAD32707.1};
DE SubName: Full=Putative Ras-related protein Rab4 {ECO:0000313|EMBL:PWV02534.1};
GN Name=RAB7 {ECO:0000313|EMBL:AAD32707.1};
GN ORFNames=C4B63_2g161 {ECO:0000313|EMBL:PWV02534.1};
OS Trypanosoma cruzi.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=5693 {ECO:0000313|EMBL:AAD32707.1};
RN [1] {ECO:0000313|EMBL:AAD32707.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Dm28c {ECO:0000313|EMBL:AAD32707.1};
RA Leal S.T.G., Araripe J.R., Urmenyi T., Cross G.A.M., Rondinelli E.;
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAD32707.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Dm28c {ECO:0000313|EMBL:AAD32707.1};
RX PubMed=11038317; DOI=10.1006/expr.2000.4549;
RA Leal S.T., Araripe J.R., Urmenyi T.P., Cross G.A., Rondinelli E.;
RT "Trypanosoma cruzi: cloning and characterization of a RAB7 gene.";
RL Exp. Parasitol. 96:23-31(2000).
RN [3] {ECO:0000313|EMBL:PWV02534.1, ECO:0000313|Proteomes:UP000246121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:PWV02534.1,
RC ECO:0000313|Proteomes:UP000246121};
RX PubMed=29708484;
RA Berna L., Rodriguez M., Chiribao M.L., Parodi-Talice A., Pita S., Rijo G.,
RA Alvarez-Valin F., Robello C.;
RT "Expanding an expanded genome: long-read sequencing of Trypanosoma cruzi.";
RL Microb. Genom. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF146042; AAD32707.1; -; Genomic_DNA.
DR EMBL; PRFA01000002; PWV02534.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9XZK0; -.
DR VEuPathDB; TriTrypDB:BCY84_14176; -.
DR VEuPathDB; TriTrypDB:C3747_1g173; -.
DR VEuPathDB; TriTrypDB:C4B63_2g161; -.
DR VEuPathDB; TriTrypDB:ECC02_001296; -.
DR VEuPathDB; TriTrypDB:Tc_MARK_4382; -.
DR VEuPathDB; TriTrypDB:TcBrA4_0061280; -.
DR VEuPathDB; TriTrypDB:TcCL_NonESM00122; -.
DR VEuPathDB; TriTrypDB:TcCLB.508461.270; -.
DR VEuPathDB; TriTrypDB:TcCLB.510911.30; -.
DR VEuPathDB; TriTrypDB:TCDM_00086; -.
DR VEuPathDB; TriTrypDB:TcG_04706; -.
DR VEuPathDB; TriTrypDB:TCSYLVIO_005757; -.
DR VEuPathDB; TriTrypDB:TcYC6_0070230; -.
DR Proteomes; UP000246121; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01862; Rab7; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47981; RAB FAMILY; 1.
DR PANTHER; PTHR47981:SF20; RAB FAMILY; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
SQ SEQUENCE 221 AA; 23843 MW; D689FDCDBAD7C2B2 CRC64;
MSSKRQLLKI IILGDSGVGK TSLMHQYVNK KFDSRYKATI GADFLTKDLE LNGQLVTLQI
WDTAGQERFQ SLGSAFYRGA DACILVFDVT QQESFSHISS WLEEFNIQAG KRDSVLIGNK
TDLADRRQVA SKTAQAWCAA QSGEAAAASG GSSITASGSG GCCMRYFETS AKENTGVEEA
FIAIATAALA QRATVDEDVV LPQSVNLSQP APREKKQNCL C
//
