ID Q9ZD64_RICPR Unreviewed; 591 AA.
AC Q9ZD64;
DT 01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1999, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Xaa-Pro aminopeptidase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=RP482 {ECO:0000313|EMBL:CAA14935.1};
OS Rickettsia prowazekii (strain Madrid E).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX NCBI_TaxID=272947 {ECO:0000313|EMBL:CAA14935.1, ECO:0000313|Proteomes:UP000002480};
RN [1] {ECO:0000313|EMBL:CAA14935.1, ECO:0000313|Proteomes:UP000002480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E {ECO:0000313|EMBL:CAA14935.1,
RC ECO:0000313|Proteomes:UP000002480};
RX PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.S., Winkler H.H.,
RA Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; AJ235272; CAA14935.1; -; Genomic_DNA.
DR PIR; E71651; E71651.
DR RefSeq; NP_220859.1; NC_000963.1.
DR RefSeq; WP_004599501.1; NC_000963.1.
DR AlphaFoldDB; Q9ZD64; -.
DR SMR; Q9ZD64; -.
DR STRING; 272947.gene:17555562; -.
DR EnsemblBacteria; CAA14935; CAA14935; CAA14935.
DR GeneID; 57569607; -.
DR KEGG; rpr:RP482; -.
DR PATRIC; fig|272947.5.peg.492; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_4_5; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000002480; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002480}.
FT DOMAIN 5..120
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 335..523
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 527..582
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 591 AA; 67869 MW; E02844CDE349A0D7 CRC64;
MRHDRINLLR KLFIEYNIEG YIIPSNDKYM NEYVPEYAKR LEYITGFTGS SGIAIICKDA
AFFFTDGRYL EQANKELDLA FYKIYDLKEI YKTLDKNIKI GYDPQLFTYQ VLANLNINFH
KINENLVDKI WYNKPLEPNS KVYLHDIKFA GVSHNDKIRK CRETILSSSS VTVGCNKNND
DILVILDSAS ICWLLNLRAS DVNYTPLMFA KVILTSTKLY LFINPIRIDT EIINARPEIT
ILPEKEFENI LRDSKNRYLI DDSITSVHIM DLIANKKVKK IVEPCLLAKA CKNDIEIKHA
IDFHIKDAVA LCEFFAEFFL YHSSENVNSC FHSHEIITEH SLCLKLTAQR AKQEGYVSDS
FHAICGFQEN SAIIHYRANP KTAKKIEGHG ILLIDSGAQY KGATTDITRT IIVGIPTCEQ
KKRYTQVLKG HIALTRAKFP KNIVTGANLD ILARQYLWQD MIDYPHGTGH GVGSFLSVHE
GPQSINLSNK IILKAGMILS NEPGFYIPGK YGIRIENLIY VKENNGWLEF ETLSLVPYAS
KLIDVALLNI DEINYIKEYY NKIRAKIYNL LSTQAKYWLN YEINLFLQSL L
//
